Ma Jingfei
Department of Imaging Physics, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
J Magn Reson Imaging. 2008 Apr;27(4):881-90. doi: 10.1002/jmri.21281.
To develop a single-point Dixon (SPD) technique that requires only data of a single echo with a flexible echo time, and to demonstrate its use for fat-suppressed, T1-weighted contrast agent enhancement studies.
Raw data were collected using a product fast 3D gradient-echo pulse sequence. Phase-error removal and fat-suppression (FS) were achieved using a fully-automated region-growing algorithm. A water and fat phantom and the abdomen and breast of cancer patients before and after injection of gadolinium contrast agent were imaged at varying echo times. Scan time efficiency and overall FS quality were compared to those by the product fast 3D gradient-echo technique with conventional FS.
In phantom, the SPD technique achieved uniform FS for a wide range of echo times corresponding to the water and fat relative phase angles between 100 degrees and 160 degrees. In patients, the technique was able to achieve approximately 30% scan time reduction and more uniform FS when compared to using the conventional FS technique but otherwise identical scan parameters.
The SPD technique compares favorably in scan time efficiency and FS uniformity and can be useful for fast T1-weighted and fat-suppressed imaging with contrast agent administration.
开发一种单点狄克逊（SPD）技术，该技术仅需要具有灵活回波时间的单个回波的数据，并证明其在脂肪抑制的T1加权造影剂增强研究中的应用。
使用商用快速3D梯度回波脉冲序列采集原始数据。使用全自动区域生长算法实现相位误差消除和脂肪抑制（FS）。在不同的回波时间对水脂模体以及癌症患者注射钆造影剂前后的腹部和乳房进行成像。将扫描时间效率和整体FS质量与采用传统FS的商用快速3D梯度回波技术进行比较。
在模体中，SPD技术在对应于水和脂肪相对相位角在100度至160度之间的广泛回波时间范围内实现了均匀的FS。在患者中，与使用传统FS技术但扫描参数相同的情况相比，该技术能够将扫描时间减少约30%，并实现更均匀的FS。
SPD技术在扫描时间效率和FS均匀性方面表现良好，可用于注射造影剂后的快速T1加权和脂肪抑制成像。
