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干酪乳杆菌 BL23 双组分信号转导系统对其耐受应激条件的影响。

Influence of two-component signal transduction systems of Lactobacillus casei BL23 on tolerance to stress conditions.

机构信息

Departamento de Biotecnología de Alimentos, Instituto de Agroquímica y Tecnología de Alimentos, Consejo Superior de Investigaciones Científicas, P.O. Box 73, 46100 Burjassot, Valencia, Spain.

出版信息

Appl Environ Microbiol. 2011 Feb;77(4):1516-9. doi: 10.1128/AEM.02176-10. Epub 2010 Dec 23.

DOI:10.1128/AEM.02176-10
PMID:21183633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3067228/
Abstract

Lactobacillus casei BL23 carries 17 two-component signal transduction systems. Insertional mutations were introduced into each gene encoding the cognate response regulators, and their effects on growth under different conditions were assayed. Inactivation of systems TC01, TC06, and TC12 (LCABL_02080-LCABL_02090, LCABL_12050-LCABL_12060, and LCABL_19600-LCABL_19610, respectively) led to major growth defects under the conditions assayed.

摘要

干酪乳杆菌 BL23 携带 17 个双组分信号转导系统。将插入突变引入每个编码同源应答调节剂的基因中,并测定它们在不同条件下生长的影响。TC01、TC06 和 TC12 系统(LCABL_02080-LCABL_02090、LCABL_12050-LCABL_12060 和 LCABL_19600-LCABL_19610)的失活导致在所测定的条件下出现严重的生长缺陷。

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Requirement of the Lactobacillus casei MaeKR two-component system for L-malic acid utilization via a malic enzyme pathway.通过苹果酸酶途径利用 L-苹果酸对干酪乳杆菌 MaeKR 双组份系统的需求。
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Knockout of three-component regulatory systems reveals that the apparently constitutive plantaricin-production phenotype shown by Lactobacillus plantarum on solid medium is regulated via quorum sensing.对三组分调控系统的敲除表明,植物乳杆菌在固体培养基上表现出的明显组成型植物乳杆菌素产生表型是通过群体感应进行调控的。
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