干酪乳杆菌 BL23 双组分信号转导系统对其耐受应激条件的影响。
Influence of two-component signal transduction systems of Lactobacillus casei BL23 on tolerance to stress conditions.
机构信息
Departamento de Biotecnología de Alimentos, Instituto de Agroquímica y Tecnología de Alimentos, Consejo Superior de Investigaciones Científicas, P.O. Box 73, 46100 Burjassot, Valencia, Spain.
出版信息
Appl Environ Microbiol. 2011 Feb;77(4):1516-9. doi: 10.1128/AEM.02176-10. Epub 2010 Dec 23.
Abstract
Lactobacillus casei BL23 carries 17 two-component signal transduction systems. Insertional mutations were introduced into each gene encoding the cognate response regulators, and their effects on growth under different conditions were assayed. Inactivation of systems TC01, TC06, and TC12 (LCABL_02080-LCABL_02090, LCABL_12050-LCABL_12060, and LCABL_19600-LCABL_19610, respectively) led to major growth defects under the conditions assayed.
摘要
干酪乳杆菌 BL23 携带 17 个双组分信号转导系统。将插入突变引入每个编码同源应答调节剂的基因中，并测定它们在不同条件下生长的影响。TC01、TC06 和 TC12 系统（LCABL_02080-LCABL_02090、LCABL_12050-LCABL_12060 和 LCABL_19600-LCABL_19610）的失活导致在所测定的条件下出现严重的生长缺陷。
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