Department of Molecular Phytopathology, Christian-Albrechts-University of Kiel, Hermann, Kiel, Germany.
J Bacteriol. 2011 Mar;193(5):1276-7. doi: 10.1128/JB.01351-10. Epub 2010 Dec 23.
Bacillus subtilis is an aerobic spore-forming Gram-positive bacterium that is a model organism and of great industrial significance as the source of diverse novel functional molecules. Here we present, to our knowledge, the first genome sequence of Bacillus subtilis strain gtP20b isolated from the marine environment. A subset of candidate genes and gene clusters were identified, which are potentially involved in production of diverse functional molecules, like novel ribosomal and nonribosomal antimicrobial peptides. The genome sequence described in this paper is due to its high strain specificity of great importance for basic as well as applied researches on marine organisms.
枯草芽孢杆菌是一种需氧、产芽孢的革兰氏阳性菌,它是一种模式生物,也是一种具有重要工业意义的微生物,因为它是多种新型功能分子的来源。在这里,我们展示了一株从海洋环境中分离得到的枯草芽孢杆菌菌株 gtP20b 的基因组序列,这是我们所知的首例。我们鉴定了一组候选基因和基因簇,它们可能参与了多种功能分子的产生,如新型核糖体和非核糖体抗菌肽。本文所描述的基因组序列因其菌株特异性高,对于海洋生物的基础研究和应用研究都具有重要意义。