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526 例因复发性憩室炎而行腹腔镜乙状结肠切除术的术中及术后并发症的预测性风险因素:多因素分析。

Predictive risk factors for intra- and postoperative complications in 526 laparoscopic sigmoid resections due to recurrent diverticulitis: a multivariate analysis.

机构信息

Department of Surgery, City Hospital Waid, Tièche-Strasse 99, 8037 Zurich, Switzerland.

出版信息

World J Surg. 2011 Mar;35(3):677-83. doi: 10.1007/s00268-010-0889-2.

Abstract

BACKGROUND

Laparoscopic sigmoid resection is a feasible and frequent operation for patients who suffer from recurrent diverticulitis. There is still an ongoing debate about the optimal timing for surgery in patients who suffer from recurrent diverticulitis episodes. In elective situations the complication rate for this procedure is moderate, but there are patients at high risk for perioperative complications. The few identified risk factors so far refer to open surgery. Data for the elective laparoscopic approach is rare. The objective of this study was to identify potential predictive risk factors for intra- and postoperative complications in patients who underwent laparoscopic sigmoid resection due to diverticular disease.

METHODS

Uni- and multivariate analyses of a prospectively gathered database (1993-2006) were performed on a consecutive series of 526 patients who underwent laparoscopic sigmoid resection due to recurrent diverticulitis in a single institution. Patients were assessed for demographic data, operative indications, and intra- and postoperative complications. Altogether, we analyzed 17 potential risk factors to identify significant influence on the intra- and postoperative outcome, including timing of surgery.

RESULTS

Statistical analysis of specific medical and surgical complications revealed anemia, previous myocardial infarction, heart failure, experience of the surgeon, and male gender, as independent predictive risk factors for postoperative complications. Patients older than age 75 years was the only independent risk factor for intraoperative complications in a multiple logistic regression model. Early elective surgery led to increased conversion rate but did not influence the postoperative complication rate.

CONCLUSIONS

This large, single-center study provides first evidence of the significance of specific predictive risk factors for intra- and postoperative complications in laparoscopic sigmoid resection for diverticular disease.

摘要

背景

腹腔镜乙状结肠切除术是治疗复发性憩室炎患者的一种可行且常见的手术。对于复发性憩室炎患者,手术的最佳时机仍存在争议。在择期手术的情况下,该手术的并发症发生率中等,但有些患者存在围手术期并发症的高风险。迄今为止,少数已确定的风险因素与开放手术有关。对于择期腹腔镜方法的数据很少。本研究的目的是确定因憩室疾病而行腹腔镜乙状结肠切除术的患者术中及术后并发症的潜在预测性危险因素。

方法

对一家单机构连续收集的数据库(1993-2006 年)中的 526 例因复发性憩室炎而行腹腔镜乙状结肠切除术的患者进行了单变量和多变量分析。对患者的人口统计学数据、手术适应证以及术中及术后并发症进行了评估。我们总共分析了 17 个潜在的危险因素,以确定对术中及术后结果有显著影响的因素,包括手术时机。

结果

对特定的医疗和手术并发症进行统计学分析发现,贫血、既往心肌梗死、心力衰竭、手术医生的经验和男性是术后并发症的独立预测危险因素。在多变量逻辑回归模型中,年龄大于 75 岁的患者是术中并发症的唯一独立危险因素。早期择期手术会增加中转率,但不会影响术后并发症发生率。

结论

这项大型单中心研究首次提供了证据,证明了在因憩室疾病而行腹腔镜乙状结肠切除术的患者中,特定的预测性危险因素对术中及术后并发症具有重要意义。

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