Chen Hongling, Liu Lifang, Lin Hongjie, Geng Yiqun, Zhang Mingzhi
Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong,Shantou 515041,China.
Yan Ke Xue Bao. 2010 Nov;25(2):103-6. doi: 10.3969/g.issn.1000-4432.2010.02.011.
To study the characteristics of photopic flash electroretinogram (ERG) in normal adult SD rats.
Sixty normal adult SD rats aged 9 to 12 weeks were enrolled in this study. Photopic flash ERG were recorded from these 60 SD rats. The results were statistically analyzed with SPSS software.
Stable a, b and PhNR wave could be recorded in each rat. Implicit time of a wave, implicit time and amplitude of PhNR fit normal distribution. Implicit time of PhNR was (124.6±8.5) ms with the smallest coefficient of variation of 0.07. The amplitude of PhNR was (11.3±4.2) μV and coefficient of variation was 0.37. There was no difference in the results between female and male rats.
Photopic flash ERG is an objective method in evaluating the retinal function in SD rats and PhNR can be used as a sensitive index of inner retinal function.