Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan.
Org Lett. 2011 Feb 4;13(3):362-5. doi: 10.1021/ol102927y. Epub 2010 Dec 27.
The concise synthesis of axially chiral biaryl diphosphine ligands by the rhodium-catalyzed intramolecular [2 + 2 + 2] cycloaddition of hexayne diphosphine oxides has been achieved. These new chiral diphosphine ligands could be employed as a ligand for the rhodium-catalyzed asymmetric catalyses.
通过铑催化的己二炔二膦氧化物的分子内[2 + 2 + 2]环加成反应，实现了轴向手性联芳基二膦配体的简洁合成。这些新的手性二膦配体可用作铑催化不对称催化的配体。
