Jhamb Swaty, Nikhil Vineeta, Singh Vijay
Department of Conservative Dentistry and Endodontics, Dr. H S Judge Institute of Dental Sciences, Chandigarh, India.
Indian J Dent Res. 2010 Oct-Dec;21(4):512-4. doi: 10.4103/0970-9290.74222.
To evaluate and compare the antibacterial effects of chlorhexidine and calcium hydroxide on Enterococcus faecalis.
Root canal treatment involves a number of steps. In spite of all the steps done thoroughly, root canal treatment might fail due to the remnant microbes. Of all such bacteria, E. faecalis is found in failed root canals. The study tests the antibacterial activity of various intracanal medicaments. Agar diffusion test was used to evaluate the antibacterial effects of the following antibacterial agents: i. hexidine:0.2% chlorhexidine gluconate; ii. periogard:0.12% chlorhexidine gluconate; iii. calcium hydroxide powder plus sterile water; iv. metapaste plus sterile water; v. calcium hydroxide plus hexidine; vi. calcium hydroxide plus periogard; vii. metapaste plus hexidine; viii. metapaste plus periogard. The size of zones of inhibition was measured.
The average size of zones of inhibition after 72 hours were hexidine: 5 mm; periogard: 4.25 mm; calcium hydroxide plus sterile water: 0.5 mm; metapaste plus sterile water: 0.5 mm; calcium hydroxide plus hexidine: 4.7 mm; calcium hydroxide plus periogard: 4 mm; metapaste plus hexidine: 4.65 mm; metapaste plus periogard: 4 mm. Results were subjected to statistical analysis using one way analysis of variance and Tukey tests.
Chlorhexidine and its preparations are more potent antibacterial agents against E. faecalis in comparison to calcium hydroxide.
评估和比较洗必泰和氢氧化钙对粪肠球菌的抗菌效果。
根管治疗包括多个步骤。尽管所有步骤都已彻底完成，但由于残留微生物，根管治疗仍可能失败。在所有这些细菌中，粪肠球菌存在于失败的根管中。本研究测试了各种根管内药物的抗菌活性。采用琼脂扩散试验评估以下抗菌剂的抗菌效果：i. 洗必泰：0.2%葡萄糖酸氯己定；ii. 派丽奥：0.12%葡萄糖酸氯己定；iii. 氢氧化钙粉末加无菌水；iv. 甲硝唑糊剂加无菌水；v. 氢氧化钙加洗必泰；vi. 氢氧化钙加派丽奥；vii. 甲硝唑糊剂加洗必泰；viii. 甲硝唑糊剂加派丽奥。测量抑菌圈大小。
72小时后抑菌圈的平均大小分别为：洗必泰：5毫米；派丽奥：4.25毫米；氢氧化钙加无菌水：0.5毫米；甲硝唑糊剂加无菌水：0.5毫米；氢氧化钙加洗必泰：4.7毫米；氢氧化钙加派丽奥：4毫米；甲硝唑糊剂加洗必泰：4.65毫米；甲硝唑糊剂加派丽奥：4毫米。结果采用单因素方差分析和Tukey检验进行统计分析。
与氢氧化钙相比，洗必泰及其制剂对粪肠球菌是更有效的抗菌剂。
