Campanelli Giampiero, Pettinari Diego, Cavalli Marta, Avesani Ettore Contessini
Department of Surgical Sciences, University of Milano, Policlinico Hospital I.R.C.C.S, Pad. Beretta Est, Milano, Italy.
J Minim Access Surg. 2006 Sep;2(3):129-33. doi: 10.4103/0972-9941.27724.
In recent years, general surgeons who perform inguinal hernia repair have paid attention to successful reduction in the recurrence rate. The Lichtenstein technique is widely used because it is easy to learn and is associated with a low rate of complication and recurrences. Today, the new objective in primary hernia surgery should be to reduce complications such as chronic pain. Chronic pain after hernia repair can be disabling, with considerable impact on quality of life and there is evidence to suggest increased use of health services by patients who have chronic pain. We have proposed an international randomized controlled trial with seven referenced European centers: The TI.ME.LI. trial. The aim of this study is to evaluate pain and further disabling complications in patients undergoing Lichtenstein technique for primary inguinal hernia repair by fixing the mesh with fibrin sealant versus sutures (control group).
近年来，进行腹股沟疝修补术的普通外科医生一直关注如何成功降低复发率。利希滕斯坦技术被广泛应用，因为它易于学习，且并发症和复发率较低。如今，原发性疝手术的新目标应是减少诸如慢性疼痛等并发症。疝修补术后的慢性疼痛可能使人致残，对生活质量有相当大的影响，而且有证据表明，患有慢性疼痛的患者会更多地使用医疗服务。我们已经提议开展一项有7个欧洲参考中心参与的国际随机对照试验：即TI.ME.LI.试验。本研究的目的是，通过使用纤维蛋白密封剂固定补片与使用缝线固定补片（对照组），来评估接受利希滕斯坦技术进行原发性腹股沟疝修补术的患者的疼痛情况及其他致残性并发症。
