Mistry B, Medhane Dipti, Mohanraj Krishnapriya, Ghone Sanjeevani A
Department of Pharmaceutical Chemistry, Bombay College of Pharmacy, Kalina, Santacruz (E) Mumbai - 400 098, India.
Indian J Pharm Sci. 2010 May;72(3):378-80. doi: 10.4103/0250-474X.70489.
Rapid and efficient methods for the synthesis of an important intermediate of benazepril ethyl 3-phthalimido-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one-1-acetate under the influence of microwave irradiation are described. A comparative study of conventional and microwave assisted method is briefly discussed.
描述了在微波辐射影响下快速高效合成贝那普利重要中间体3-邻苯二甲酰亚氨基-2,3,4,5-四氢-1H-[1]苯并氮杂䓬-2-酮-1-乙酸乙酯的方法。简要讨论了传统方法与微波辅助方法的对比研究。