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本文引用的文献

1
Synthesis and biological properties of (carboxyalkyl)amino-substituted bicyclic lactam inhibitors of angiotensin converting enzyme.血管紧张素转换酶的(羧基烷基)氨基取代双环内酰胺抑制剂的合成及生物学性质
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微波辅助合成贝那普利的重要中间体

Microwave-assisted Synthesis of an Important Intermediate of Benazepril.

作者信息

Mistry B, Medhane Dipti, Mohanraj Krishnapriya, Ghone Sanjeevani A

机构信息

Department of Pharmaceutical Chemistry, Bombay College of Pharmacy, Kalina, Santacruz (E) Mumbai - 400 098, India.

出版信息

Indian J Pharm Sci. 2010 May;72(3):378-80. doi: 10.4103/0250-474X.70489.

DOI:10.4103/0250-474X.70489
PMID:21188052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3003176/
Abstract

Rapid and efficient methods for the synthesis of an important intermediate of benazepril ethyl 3-phthalimido-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one-1-acetate under the influence of microwave irradiation are described. A comparative study of conventional and microwave assisted method is briefly discussed.

摘要

描述了在微波辐射影响下快速高效合成贝那普利重要中间体3-邻苯二甲酰亚氨基-2,3,4,5-四氢-1H-[1]苯并氮杂䓬-2-酮-1-乙酸乙酯的方法。简要讨论了传统方法与微波辅助方法的对比研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e7/3003176/83df944e8121/IJPhS-72-378-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e7/3003176/932d38ae2ee7/IJPhS-72-378-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e7/3003176/83df944e8121/IJPhS-72-378-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e7/3003176/932d38ae2ee7/IJPhS-72-378-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e7/3003176/83df944e8121/IJPhS-72-378-g002.jpg