Ratterree William O, Glassman Mathieu M, Driskell Elizabeth A, Havig Marc E
Department of Veterinary Clinical Sciences, Louisiana State University, School of Veterinary Medicine, Baton Rouge, LA, USA.
J Am Anim Hosp Assoc. 2011 Jan-Feb;47(1):e7-12. doi: 10.5326/JAAHA-MS-5464. Epub 2010 Dec 16.
This report describes a 4 mo old intact male Akita that presented for evaluation of a life-long history of facial swelling and failure to thrive. Physical examination revealed an enlarged cranium with prominent bony swellings on the maxillary bone, excessive laxity and crepitus involving multiple joints, and proprioceptive deficits. Radiographs demonstrated multiple osseous abnormalities including endosteal thickening of the femurs and ilium. Necropsy revealed gross compression of the cerebellum and brainstem. Physical exam findings, radiographic abnormalities, and histopathology of multiple bony lesions were all consistent with craniomandibular osteopathy. In this unique case of craniomandibular osteopathy, the dog was affected with severe bony proliferations leading to generalized hyperostotic lesions and brainstem compression resulting in neurologic deficits.
本报告描述了一只4月龄未绝育的雄性秋田犬，该犬因面部肿胀和发育不良的终生病史前来接受评估。体格检查发现颅骨增大，上颌骨有明显的骨质肿胀，多个关节过度松弛并伴有捻发音，以及本体感觉缺陷。X线片显示多个骨质异常，包括股骨和髂骨的骨内膜增厚。尸检发现小脑和脑干受到明显压迫。体格检查结果、X线异常以及多个骨病变的组织病理学均与颅下颌骨病相符。在这例独特的颅下颌骨病病例中，该犬患有严重的骨质增生，导致全身普遍性骨肥厚性病变和脑干受压，进而出现神经功能缺损。
