Le Guen P-Y, Gestin S, Plat E, Quéhé P, Bressollette L
Unité d'écho-doppler et de médecine vasculaire, CHU La Cavale-Blanche, boulevard Tanguy-Prigent, Brest cedex, France.
J Mal Vasc. 2011 Feb;36(1):41-4. doi: 10.1016/j.jmv.2010.11.003. Epub 2010 Dec 28.
Cannabis is the most widely consumed drug in the world, particularly among young subjects. Cocaine is the third leading illicit drug. Cases of renal infarction associated with combined consumption of cannabis and cocaine have been reported in the literature. We describe the case of a 24-year-old man who presented renal and spleen infarction after massive consumption of cannabis and cocaine. Both vascular events arose on healthy arteries. Etiological tests were negative leading to the conclusion that the events resulted from a toxic cause related to cannabis and cocaine consumption. Different mechanisms, potentially including thrombosis, might explain the association of cannabis and cocaine with vascular events. We suggest that a systematic search for cannabis and cocaine consumption among young victims of vascular disease might be useful.
大麻是世界上消费最为广泛的毒品,在年轻人群体中尤为如此。可卡因是第三大主要非法毒品。文献中已有与大麻和可卡因联合使用相关的肾梗死病例报道。我们描述了一名24岁男性的病例,该患者在大量吸食大麻和可卡因后出现了肾梗死和脾梗死。这两种血管事件均发生在健康动脉上。病因学检查呈阴性,得出的结论是这些事件是由与大麻和可卡因消费相关的毒性原因导致的。不同机制,可能包括血栓形成,或许可以解释大麻和可卡因与血管事件之间的关联。我们建议,在年轻的血管疾病受害者中系统地排查大麻和可卡因消费情况可能会有所帮助。