Ruhmann-Wennhold A, Nelson D H
Ann N Y Acad Sci. 1977 Oct 28;297:498-508. doi: 10.1111/j.1749-6632.1977.tb41877.x.
Following adrenalectomy there is a triphasic response of ACTH secretion characterized by an initial high rise immediately following the adrenalectomy, secondary to the stress of the procedure. This is followed by a fall to resting ACTH secretion until a steady state is reached 1 to 2 weeks following adrenalectomy at levels about 10 times normal. The ability to respond to stress with increased ACTH secretion is not lost at any time following adrenalectomy.
肾上腺切除术后，促肾上腺皮质激素（ACTH）分泌会出现三相反应，其特征为肾上腺切除术后立即因手术应激而出现最初的急剧升高。随后下降至静息ACTH分泌水平，直到肾上腺切除术后1至2周达到稳定状态，此时的水平约为正常水平的10倍。肾上腺切除术后任何时候，ACTH分泌增加以应对应激的能力都不会丧失。
