印度尼西亚两个不同民族社区猪和人群中戊型肝炎病毒的流行情况。

Prevalence of hepatitis E virus among swine and humans in two different ethnic communities in Indonesia.

机构信息

Indonesia-Japan Collaborative Research Center for Emerging and Re-emerging Infectious Diseases, Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia.

出版信息

Arch Virol. 2011 Apr;156(4):689-93. doi: 10.1007/s00705-010-0883-x. Epub 2010 Dec 30.

DOI:10.1007/s00705-010-0883-x

PMID:21191625

Abstract

The purpose of this study was to investigate the prevalence of hepatitis E virus (HEV) infection in swine and humans in different environments in Java and Bali, Indonesia. The prevalence of anti-HEV antibodies in people over 20 years old living in communities in Bali was significantly higher than that in Java. While 68.8% and 90.0% of swine in Bali were anti-HEV positive at 1 and 2 months of age, respectively, swine in Java were at significantly lower risk of HEV infection by the age of 2 months. Our present data suggest that substantial differences in swine-breeding conditions and human living environments affect the rate of HEV infection in humans and swine.

摘要

本研究旨在调查印度尼西亚爪哇岛和巴厘岛不同环境中猪和人类感染戊型肝炎病毒（HEV）的流行情况。在巴厘岛社区居住的 20 岁以上人群中，抗-HEV 抗体的流行率明显高于爪哇岛。在 1 月龄和 2 月龄时，巴厘岛的猪抗-HEV 阳性率分别为 68.8%和 90.0%，而爪哇岛的猪在 2 月龄时感染 HEV 的风险明显较低。本研究数据表明，猪养殖条件和人类生活环境的显著差异影响了人类和猪的 HEV 感染率。