Chemistry Department, INQUISUR, National University of South- CONICET, Alem Av 1253, 8000 Bahia Blanca, Argentina.
Front Biosci (Landmark Ed). 2011 Jan 1;16(1):61-73. doi: 10.2741/3676.
In this review, we shall outline the basic principles of circular dichroism (CD) indicating the types of structural information relevant to the study of biomolecules, such as proteins or DNA. We are mainly interested to show the utility of this technique to study protein-ligand, DNA-ligand and protein-DNA interactions.
在这篇综述中,我们将概述圆二色性 (CD) 的基本原理,指出与生物分子(如蛋白质或 DNA)研究相关的结构信息类型。我们主要感兴趣的是展示该技术在研究蛋白-配体、DNA-配体和蛋白-DNA 相互作用方面的应用。