Mijovic Tamara, How Jacques, Payne Richard J
Department of Otolaryngology and Head and Neck Surgery, McGill University, Montreal, Quebec, Canada.
Front Biosci (Schol Ed). 2011 Jan 1;3(2):555-64. doi: 10.2741/s171.
With the current trend of alarming rise in obesity rates, the health impacts of excess weight will become more apparent. While an increased incidence of cardiovascular disease and diabetes mellitus has been well documented, the association between obesity and carcinogenesis is just being appreciated and is receiving increasing attention. The current review focuses on the evidence linking thyroid cancer with obesity. We conclude that there is sufficient evidence that obesity can predispose to an increased risk of thyroid cancer in both men and women. This population-based association is mainly explained at a biological level through specific obesity-related endocrinopathies.
随着当前肥胖率惊人上升的趋势,超重对健康的影响将变得更加明显。虽然心血管疾病和糖尿病发病率的增加已有充分记录,但肥胖与致癌作用之间的关联才刚刚被认识到,并受到越来越多的关注。本综述聚焦于将甲状腺癌与肥胖联系起来的证据。我们得出结论,有充分证据表明肥胖会使男性和女性患甲状腺癌的风险增加。这种基于人群的关联主要在生物学层面通过特定的肥胖相关内分泌疾病来解释。