Rios D, Capin R, Ortíz-Ortíz L
Arch Invest Med (Mex). 1978;9 Suppl 1:303-8.
The immune response in hamsters either infected or immunized with Entamoeba histolytica was studied. The response was tested by determination of antibodies by the counterimmunoelectrophoresis technique and by lymphocyte transformation induced by the amebic antigen. The results obtained showed differences among both groups when the ability of amebic antigen to induce 3H-thymidine incorporation of lymphocyte cultures is compared. However, the response of lymphocyte cultures to Concanavalin A was similar in both studied groups. On the other hand, a group of hamsters hyperimmunized with E. histolytica antigen incorporated in complete Frend's adjuvant showed a greater immune response than the group receiving a single dose.
对感染或免疫溶组织内阿米巴的仓鼠的免疫反应进行了研究。通过对流免疫电泳技术测定抗体以及通过阿米巴抗原诱导淋巴细胞转化来检测该反应。当比较阿米巴抗原诱导淋巴细胞培养物掺入3H-胸腺嘧啶核苷的能力时,所获得的结果显示两组之间存在差异。然而,在两个研究组中,淋巴细胞培养物对刀豆球蛋白A的反应相似。另一方面,一组用完全弗氏佐剂掺入溶组织内阿米巴抗原进行超免疫的仓鼠,其免疫反应比接受单剂量的组更强。