Division of Occupational and Environmental Health, Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario M5T 3M7, Canada.
Occup Med (Lond). 2011 Mar;61(2):115-20. doi: 10.1093/occmed/kqq191. Epub 2010 Dec 31.
Previous studies have suggested that the presence of the vascular component of hand-arm vibration syndrome (HAVS) in the hands increases the risk of cold-induced vasospasm in the feet.
To determine if objectively measured cold-induced vasospasm in the hands is a risk factor for objectively measured cold-induced vasospasm in the feet in workers being assessed for HAVS.
The subjects were 191 male construction workers who had a standardized assessment for HAVS including cold provocation digital photocell plethysmography of the hands and feet to measure cold-induced vasospasm. Bivariate analysis and multinomial logistic regression were used to examine the association between plethysmographic findings in the feet and predictor variables including years worked in construction, occupation, current smoking, cold intolerance in the feet, the Stockholm vascular stage and plethysmographic findings in the hands.
Sixty-one (32%) subjects had non-severe vasospasm and 59 (31%) had severe vasospasm in the right foot with the corresponding values being 57(30%) and 62 (32%) in the left foot. Multinomial logistic regression indicated that the only statistically significant predictor of severe vasospasm in the feet was the presence of severe vasospasm in the hands (OR: 4.11, 95% CI: 1.60-10.6, P < 0.01 on the right side and OR: 4.97, 95% CI: 1.82-13.53, P < 0.01 on the left side). Multinomial logistic regression analysis did not indicate any statistically significant predictors of non-severe vasospasm in the feet.
Workers assessed for HAVS frequently have cold-induced vasospasm of their feet. The main predictor of severe vasospastic foot abnormalities is severe cold-induced vasospasm in the hands.
先前的研究表明,手部的手臂振动综合征(HAVS)血管成分的存在会增加脚部冷诱发血管痉挛的风险。
确定手部客观测量的冷诱发血管痉挛是否是接受 HAVS 评估的工人脚部客观测量的冷诱发血管痉挛的危险因素。
研究对象为 191 名男性建筑工人,他们接受了 HAVS 的标准化评估,包括手部和脚部的冷激发数字光电容积描记法来测量冷诱发血管痉挛。使用双变量分析和多项逻辑回归来检查脚部光电容积描记法结果与预测变量之间的关联,包括在建筑行业工作的年限、职业、当前吸烟状况、脚部对寒冷的不耐受性、斯德哥尔摩血管分期以及手部光电容积描记法结果。
61 名(32%)受试者的右脚出现非严重血管痉挛,59 名(31%)受试者的右脚出现严重血管痉挛,相应的左脚数据为 57 名(30%)和 62 名(32%)。多项逻辑回归表明,脚部严重血管痉挛的唯一具有统计学意义的预测因子是手部严重血管痉挛(右侧 OR:4.11,95%CI:1.60-10.6,P<0.01;左侧 OR:4.97,95%CI:1.82-13.53,P<0.01)。多项逻辑回归分析并未表明脚部非严重血管痉挛的任何具有统计学意义的预测因子。
接受 HAVS 评估的工人经常出现脚部冷诱发血管痉挛。严重冷诱发手部血管痉挛是脚部严重血管痉挛异常的主要预测因子。