自组装单分子层中嵌入的DNA碱基电导的识别隧穿测量。
Recognition tunneling measurement of the conductance of DNA bases embedded in self-assembled monolayers.
作者信息
Huang Shuo, Chang Shuai, He Jin, Zhang Peiming, Liang Feng, Tuchband Michael, Li Shengqing, Lindsay Stuart
机构信息
Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
出版信息
J Phys Chem C Nanomater Interfaces. 2010 Dec 9;114(48):20443-20448. doi: 10.1021/jp104792s.
Abstract
The DNA bases interact strongly with gold electrodes, complicating efforts to measure the tunneling conductance through hydrogen-bonded Watson Crick base pairs. When bases are embedded in a self-assembled alkane-thiol monolayer to minimize these interactions, new features appear in the tunneling data. These new features track the predictions of density-functional calculations quite well, suggesting that they reflect tunnel conductance through hydrogen-bonded base pairs.
摘要
DNA碱基与金电极之间相互作用强烈，这使得测量通过氢键连接的沃森-克里克碱基对的隧穿电导变得复杂。当碱基嵌入自组装的烷烃硫醇单分子层中以尽量减少这些相互作用时，隧穿数据中会出现新的特征。这些新特征与密度泛函计算的预测结果吻合得很好，这表明它们反映了通过氢键连接的碱基对的隧穿电导。
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