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日本麻疹感染的母体筛查和产后疫苗接种:一项队列研究。

Maternal screening and postpartum vaccination for measles infection in Japan: a cohort study.

机构信息

Department of Obstetrics and Gynaecology, Dokkyo Medical University, Tochigi, Japan.

出版信息

BJOG. 2011 Jan;118(1):88-92. doi: 10.1111/j.1471-0528.2010.02764.x.

DOI:10.1111/j.1471-0528.2010.02764.x
PMID:21197682
Abstract

We investigated the prevalence of measles-sensitive pregnant women and the clinical usefulness of measles vaccination in postpartum women. Measles antibody levels were measured in 751 pregnant women. Forty-four women were vaccinated postpartum, and screened for antibody levels and adverse effects 1 month after vaccination. The prevalence of measles-sensitive pregnant women was 10-20%, with the highest prevalence in those under 24 years of age. Almost all (97.7%) vaccinated women acquired immunity, and did not show any adverse effects. Serum measles antibody levels should be determined in all pregnant women as a screening tool,and sensitive women should be vaccinated immediately after delivery.

摘要

我们调查了麻疹易感孕妇的流行率,以及产后妇女接种麻疹疫苗的临床效果。我们检测了 751 名孕妇的麻疹抗体水平,对其中 44 名孕妇进行了产后接种,并在接种后 1 个月检测了她们的抗体水平和不良反应。麻疹易感孕妇的流行率为 10-20%,其中 24 岁以下孕妇的流行率最高。几乎所有(97.7%)接种疫苗的妇女都获得了免疫力,且没有任何不良反应。所有孕妇都应进行血清麻疹抗体水平检测,作为筛查工具,对敏感妇女应在产后立即接种疫苗。

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PLoS One. 2013;8(1):e55043. doi: 10.1371/journal.pone.0055043. Epub 2013 Jan 31.