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钙磷酸盐涂层对兔模型中种植体骨整合的影响。

Effects of a calcium phosphate coating on the osseointegration of endosseous implants in a rabbit model.

机构信息

Department of Implant Dentistry, Università degli studi di Milano, Fondazione IRCCS Ca' Grande, Milano, ItalyDepartment of Periodontology, Università degli studi di Milano, Fondazione IRCCS Ca' Grande, Milano, ItalyCRABCC - Reseach Center on Biotechnological Applications, Università degli studi di Milano, Milano, ItalyDepartment of Periodontics, School of dental Medicine, University of Pennsylvania, Philadelphia, PA, USAPrivate Practice, Pessano con Bornago, Milano, ItalyChairman, Department of Periodontology, Università degli studi di Milano, Fondazione IRCCS Ca' Grande, Milano, Italy.

出版信息

Clin Oral Implants Res. 2011 Jul;22(7):760-766. doi: 10.1111/j.1600-0501.2010.02056.x. Epub 2010 Dec 29.

Abstract

OBJECTIVES

The aim of the present study was to evaluate a Ca-P coated implant surface in a rabbit model. The Ca-P surface (test) was compared to the titanium porous oxide surface (control) in terms of bone-to-implant contact (BIC) and removal torque value.

MATERIALS AND METHODS

Two hundred and sixteen dental implants were inserted in the tibia and in the femur of 36 rabbits. One hundred and eight were represented by Ca-P oxidized surface implant and other 108 were titanium porous oxide surface modified implants. Each rabbit received six implants. Animals were sacrificed after 2, 4 and 9 weeks of healing. Each group included 12 rabbits. The femoral implant and the proximal implant of the tibia of each animal were subjected to the histologic analysis and the distal implants of the tibia underwent removal torque test (RTQ).

RESULTS

Histological analysis in terms of BIC and RTQ did not revealed any significant difference between the Ca-P oxidized surface and the oxidized surface at 2 and 4 weeks. At 9 weeks, the oxidized surface demonstrated better results in terms of RTQ in the tibia.

CONCLUSION

In conclusion, findings from the present study suggested that the Ca-P coating had no beneficial effect in improving bonding strength at the bone-implant interface either at 2, 4 and 9 weeks.

摘要

目的

本研究旨在评估一种钙磷涂层种植体表面在兔模型中的效果。将钙磷涂层表面(实验组)与钛多孔氧化表面(对照组)在骨-种植体接触(BIC)和移除扭矩值方面进行比较。

材料和方法

将 216 个牙种植体植入 36 只兔子的胫骨和股骨中。其中 108 个为钙磷氧化表面种植体,另 108 个为钛多孔氧化表面改性种植体。每个兔子接受 6 个种植体。在愈合 2、4 和 9 周后,动物被处死。每个组包括 12 只兔子。每组中 12 只兔子的每只动物的股骨种植体和胫骨近端种植体均接受组织学分析,胫骨远端种植体接受移除扭矩测试(RTQ)。

结果

在 2 周和 4 周时,BIC 和 RTQ 分析结果表明钙磷氧化表面与氧化表面之间没有明显差异。在 9 周时,氧化表面在胫骨中的 RTQ 方面表现出更好的结果。

结论

总之,本研究结果表明,在 2、4 和 9 周时,钙磷涂层对改善骨-种植体界面的结合强度没有有益效果。

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