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慢性阻塞性肺疾病患者急性干预期间肺动脉血流的同步多普勒和热稀释评估

Simultaneous Doppler and thermodilution assessment of pulmonary artery flow during acute interventions in patients with chronic obstructive pulmonary disease.

作者信息

Torbicki A, Tramarin R, Fracchia C, Mortara A, Ambrosino N, Pozzoli M, Rampulla C, Cobelli F

机构信息

Fondazione Clinica del Lavora, Medical Center Montescano, Pavia, Italy.

出版信息

Cor Vasa. 1990;32(3):197-205.

PMID:2119934
Abstract

Subcostal pulsed wave Doppler echocardiography of the right ventricular outflow tract was used to assess pulmonary arterial flow at basal conditions and during interventions in 20 patients with chronic obstructive pulmonary disease. The changes in the pulmonary flow induced by interventions ranged from -1.5 l/min to +4.18 l/min (73% to 183% of the basal value). When considered alone, heart rate changes induced by the interventions could explain 53% of the changes in pulmonary flow measured with thermodilution. When Doppler-assessed right ventricular stroke volume changes were also considered the coefficient of determination (R) increased to 77% (r = 0.88, p less than 0.001, SEE = 12%). Doppler echocardiography was less precise in predicting absolute basal values of pulmonary artery flow (r = 0.70, p less than 0.001, SEE = 1.00 l/min), probably indicating inaccurate assessment of the diameter of the right ventricular outflow tract.

摘要

采用肋下脉冲波多普勒超声心动图对20例慢性阻塞性肺疾病患者的右心室流出道进行检查,以评估基础状态及干预过程中的肺动脉血流情况。干预引起的肺血流变化范围为-1.5升/分钟至+4.18升/分钟(为基础值的73%至183%)。单独考虑时,干预引起的心率变化可解释热稀释法测得的肺血流变化的53%。若同时考虑多普勒评估的右心室每搏量变化,则决定系数(R)增至77%(r = 0.88,p < 0.001,标准误 = 12%)。多普勒超声心动图在预测肺动脉血流绝对基础值方面准确性较差(r = 0.70,p < 0.001,标准误 = 1.00升/分钟),这可能表明对右心室流出道直径的评估不准确。

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