依泽替米贝在心血管疾病预防中的作用：缺乏证据。
Role of ezetimibe in the prevention of cardiovascular disease: absence of evidence.
机构信息
Comando Brigata Alpina "Julia", Udine, Italy.
出版信息
Arch Med Res. 2010 Nov;41(8):649-50. doi: 10.1016/j.arcmed.2010.10.008.
PMID:21199735
Abstract
Ezetimibe is a lipid-lowering agent that inhibits intestinal absorption of dietary cholesterol. It substantially lowers low-density lipoprotein cholesterol levels when used alone or in combination with statins. Although there is a growing push for the continued use of ezetimibe for the prevention of cardiovascular disease, ezetimibe studies available so far are inconsistent, without allowing use of the drug with confidence.
摘要
依泽替米贝是一种降脂药，可抑制肠道吸收膳食胆固醇。单独使用或与他汀类药物联合使用时，可显著降低低密度脂蛋白胆固醇水平。尽管人们越来越希望继续使用依泽替米贝来预防心血管疾病，但到目前为止，依泽替米贝的研究结果并不一致，无法放心使用该药。
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