Baba H, Onizuka Y, Nakao M, Fukahori M, Sato T, Sakurai Y, Tanaka H, Endo S
Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka City, Fukuoka, Japan.
Radiat Prot Dosimetry. 2011 Feb;143(2-4):528-32. doi: 10.1093/rpd/ncq511. Epub 2011 Jan 2.
In this study, microdosimetric energy distributions of secondary charged particles from the (10)B(n,α)(7)Li reaction in boron-neutron capture therapy (BNCT) field were calculated using the Particle and Heavy Ion Transport code System (PHITS). The PHITS simulation was performed to reproduce the geometrical set-up of an experiment that measured the microdosimetric energy distributions at the Kyoto University Reactor where two types of tissue-equivalent proportional counters were used, one with A-150 wall alone and another with a 50-ppm-boron-loaded A-150 wall. It was found that the PHITS code is a useful tool for the simulation of the energy deposited in tissue in BNCT based on the comparisons with experimental results.
在本研究中，使用粒子与重离子传输代码系统（PHITS）计算了硼中子俘获疗法（BNCT）中¹⁰B（n，α）⁷Li反应产生的次级带电粒子的微剂量能量分布。进行PHITS模拟以重现一项实验的几何设置，该实验在京都大学反应堆测量了微剂量能量分布，其中使用了两种组织等效正比计数器，一种仅具有A - 150壁，另一种具有含50 ppm硼的A - 150壁。基于与实验结果的比较发现，PHITS代码是模拟BNCT中组织内沉积能量的有用工具。
