利用PHITS程序对京都大学反应堆硼中子俘获疗法的中子场进行微剂量学评估。

Microdosimetric evaluation of the neutron field for BNCT at Kyoto University reactor by using the PHITS code.

作者信息

Baba H, Onizuka Y, Nakao M, Fukahori M, Sato T, Sakurai Y, Tanaka H, Endo S

机构信息

Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka City, Fukuoka, Japan.

出版信息

Radiat Prot Dosimetry. 2011 Feb;143(2-4):528-32. doi: 10.1093/rpd/ncq511. Epub 2011 Jan 2.

DOI:10.1093/rpd/ncq511

PMID:21199830

Abstract

In this study, microdosimetric energy distributions of secondary charged particles from the (10)B(n,α)(7)Li reaction in boron-neutron capture therapy (BNCT) field were calculated using the Particle and Heavy Ion Transport code System (PHITS). The PHITS simulation was performed to reproduce the geometrical set-up of an experiment that measured the microdosimetric energy distributions at the Kyoto University Reactor where two types of tissue-equivalent proportional counters were used, one with A-150 wall alone and another with a 50-ppm-boron-loaded A-150 wall. It was found that the PHITS code is a useful tool for the simulation of the energy deposited in tissue in BNCT based on the comparisons with experimental results.

摘要

在本研究中，使用粒子与重离子传输代码系统（PHITS）计算了硼中子俘获疗法（BNCT）中¹⁰B（n，α）⁷Li反应产生的次级带电粒子的微剂量能量分布。进行PHITS模拟以重现一项实验的几何设置，该实验在京都大学反应堆测量了微剂量能量分布，其中使用了两种组织等效正比计数器，一种仅具有A - 150壁，另一种具有含50 ppm硼的A - 150壁。基于与实验结果的比较发现，PHITS代码是模拟BNCT中组织内沉积能量的有用工具。