Colautti P, Moro D, Chiriotti S, Conte V, Evangelista L, Altieri S, Bortolussi S, Protti N, Postuma I
INFN, Laboratori Nazionali di Legnaro, viale dell׳Università 2, I-35020 Legnaro, PD, Italy.
INFN, Laboratori Nazionali di Legnaro, viale dell׳Università 2, I-35020 Legnaro, PD, Italy.
Appl Radiat Isot. 2014 Jun;88:147-52. doi: 10.1016/j.apradiso.2014.01.005. Epub 2014 Jan 22.
A twin TEPC with electric-field guard tubes has been constructed to be used to characterize the BNCT field of the irradiation facility of LENA reactor. One of the two mini TEPC was doped with 50ppm of (10)B in order to simulate the BNC events occurring in BNCT. By properly processing the two microdosimetric spectra, the gamma, neutron and BNC spectral components can be derived with good precision (~6%). However, direct measurements of (10)B in some doped plastic samples, which were used for constructing the cathode walls, point out the scarce accuracy of the nominal (10)B concentration value. The influence of the Boral(®) door, which closes the irradiation channel, has been measured. The gamma dose increases significantly (+51%) when the Boral(®) door is closed. The crypt-cell-regeneration weighting function has been used to measure the quality, namely the RBEµ value, of the radiation field in different conditions. The measured RBEµ values are only partially consistent with the RBE values of other BNCT facilities.
已构建了一个带有电场保护管的双管热释光个人剂量计（TEPC），用于表征莱娜反应堆辐照设施的硼中子俘获治疗（BNCT）场。两个微型TEPC中的一个掺杂了50ppm的硼 - 10，以模拟BNCT中发生的硼中子俘获事件。通过对两个微剂量谱进行适当处理，可以高精度（约6%）得出伽马、中子和硼中子俘获谱成分。然而，对用于构建阴极壁的一些掺杂塑料样品中硼 - 10的直接测量表明，标称硼 - 10浓度值的准确性较差。已测量了关闭辐照通道的博拉（Boral®）门的影响。当博拉（Boral®）门关闭时，伽马剂量显著增加（+51%）。已使用隐窝细胞再生加权函数来测量不同条件下辐射场的质量，即相对生物学效应（RBE）与剂量平均线能量（µ）的乘积（RBEµ）值。测得的RBEµ值仅部分与其他BNCT设施的RBE值一致。
