Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
J Infect Dis. 2011 Feb 15;203(4):509-12. doi: 10.1093/infdis/jiq081. Epub 2011 Jan 3.
In 2006, the Advisory Committee on Immunization Practices recommended that children routinely receive 2 varicella vaccine doses in place of the 1 dose previously recommended. This recommendation's initial impact on varicella epidemiology in Connecticut was assessed. Reported incidence and case-specific data were compared for 2005 and 2008. Varicella incidence decreased from 48.7 cases/100,000 persons in 2005 to 24.5 in 2008. Age-specific incidence decreased significantly (P < .05) among children aged 1-14 years. Reported varicella incidence has declined in Connecticut after implementation of routine 2-dose varicella vaccination for children. Continued surveillance is needed to determine the recommendation's full impact.
2006 年，免疫实践咨询委员会建议儿童常规接种 2 剂水痘疫苗，取代之前推荐的 1 剂。本研究评估了该建议对康涅狄格州水痘流行病学的初步影响。比较了 2005 年和 2008 年的报告发病率和病例特异性数据。水痘发病率从 2005 年的每 10 万人 48.7 例降至 2008 年的 24.5 例。1-14 岁儿童的年龄特异性发病率显著下降（P<.05）。康涅狄格州在为儿童常规接种 2 剂水痘疫苗后，报告的水痘发病率有所下降。需要继续监测以确定该建议的全面影响。
