质子泵抑制剂的副作用和药物相互作用：小题大做？

Proton pump inhibitor side effects and drug interactions: much ado about nothing?

机构信息

Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, CB #7080, Chapel Hill, NC 27599, USA.

出版信息

Cleve Clin J Med. 2011 Jan;78(1):39-49. doi: 10.3949/ccjm.77a.10087.

DOI:10.3949/ccjm.77a.10087

PMID:21199906

Abstract

Proton pump inhibitors (PPIs) are widely prescribed for acid-peptic disease. In general, the safety of this class of drugs has been excellent. However, in the past several years, epidemiologic studies have indicated possible risks that are biologically plausible.

摘要

质子泵抑制剂（PPIs）广泛用于治疗酸相关疾病。总的来说，该类药物的安全性非常好。然而，在过去几年中，流行病学研究表明其存在一些生物学上合理的潜在风险。