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（1'S）-4-（3,4-二氯苯基）-1'-（3,5-二甲氧基苯基）-1,2,3,4-四氢萘-2-螺-2'-吡咯里西啶-3'-螺-3''-吲哚啉-1,2''-二酮

(1'S)-4-(3,4-Dichlorophenyl)-1'-(3,5-dimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-2-spiro-2'-pyrrolizidine-3'-spiro-3''-indoline-1,2''-dione.

作者信息

Kamala E Theboral Sugi, Murugan R, Nirmala S, Sudha L, Narayanan S Sriman

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 17;64(Pt 10):o1958-9. doi: 10.1107/S1600536808028614.

DOI:10.1107/S1600536808028614
PMID:21201161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2959408/
Abstract

In the title compound C(37)H(32)Cl(2)N(2)O(4), the unsubstituted pyrrolidine ring shows a twist conformation whereas the substituted pyrrolidine ring shows an envelope conformation. The dimeth-oxy benzene ring is perpendicular to the tetra-lone ring, making a dihedral angle of 89.94 (5)°. Mol-ecules are linked into centrosymmetric dimers by N-H⋯O hydrogen bonds and the crystal structure is stabilized by C-H⋯π inter-actions and C-H⋯O hydrogen bonds. One meth-oxy group is disordered over two positions with the site occupancy factors of 0.84 (2) and 0.16 (2).

摘要

在标题化合物C(37)H(32)Cl(2)N(2)O(4)中，未取代的吡咯烷环呈扭曲构象，而取代的吡咯烷环呈信封构象。二甲氧基苯环与四氢萘环垂直，二面角为89.94 (5)°。分子通过N-H⋯O氢键连接成中心对称二聚体，晶体结构通过C-H⋯π相互作用和C-H⋯O氢键得以稳定。一个甲氧基在两个位置上无序，占有率分别为0.84 (2)和0.16 (2)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b679/2959408/c32860ba0b16/e-64-o1958-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b679/2959408/d8b7ee88710c/e-64-o1958-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b679/2959408/c32860ba0b16/e-64-o1958-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b679/2959408/d8b7ee88710c/e-64-o1958-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b679/2959408/c32860ba0b16/e-64-o1958-fig2.jpg

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