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5-氯-5''-(4-氯苄叉基)-4'-(4-氯苯基)-1',1''-二甲基二螺-[吲哚啉-3,2'-吡咯烷-3',3''-哌啶]-2,4''-二酮

5-Chloro-5''-(4-chloro-benzyl-idene)-4'-(4-chloro-phen-yl)-1',1''-dimethyldi-spiro-[indoline-3,2'-pyrrolidine-3',3''-piperidine]-2,4''-dione.

作者信息

Farag I S Ahmed, Girgis Adel S, Ramadan A A, Moustafa A M, Mabied Ahmed F

机构信息

Crystallography Laboratory, Solid State Department, Physics Division, National Research Centre, Dokki, Giza 12622, Egypt.

Pesticide Chemistry Department, National Research Centre, Dokki, Giza 12622, Egypt.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2014 Feb 28;70(Pt 3):o379-80. doi: 10.1107/S1600536814004309. eCollection 2014 Mar 1.

Abstract

The racemic title compound, C30H26Cl3N3O2, comprises two spiro links, the first connecting the piperidine and pyrrolidine rings and the other connecting the indole and pyrrolidine rings. The piperidine ring adopts a half-chair conformation, while the pyrrolidine ring has an envelope conformation with the unsubstituted C atom as the flap. The dihedral angles between the two p-Cl-substituted benzene rings and the indole ring are 33.13 (14) and 54.11 (14)°. In the crystal, mol-ecules form inversion dimers through pairs of N-H⋯O hydrogen bonds [graph set R 2 (2)(8)]. Aromatic C-H⋯O hydrogen bonds extend these dimers into a ribbon structure, enclosing R (2) 2(14) ring motifs, along the a-axis direction.

摘要

外消旋标题化合物C₃₀H₂₆Cl₃N₃O₂包含两个螺环连接,第一个连接哌啶环和吡咯烷环,另一个连接吲哚环和吡咯烷环。哌啶环呈半椅式构象,而吡咯烷环呈信封式构象,以未取代的C原子作为瓣。两个对氯取代苯环与吲哚环之间的二面角分别为33.13 (14)°和54.11 (14)°。在晶体中,分子通过N—H⋯O氢键对形成反演二聚体[图形集R 2 (2)(8)]。芳香族C—H⋯O氢键将这些二聚体沿a轴方向延伸成带状结构,包围着R (2) 2(14)环单元。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7364/3998502/b8a41ade1f29/e-70-0o379-fig1.jpg

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