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3-氧代-2-氧杂-5-氮杂双环[2.2.1]庚烷-5-羧酸叔丁酯

tert-Butyl 3-oxo-2-oxa-5-aza-bicyclo-[2.2.1]heptane-5-carboxyl-ate.

作者信息

Lechner Marie-Charlotte, Aubert Emmanuel, Guichard Gilles, Didierjean Claude

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 30;64(Pt 10):o2039. doi: 10.1107/S1600536808030651.

DOI:10.1107/S1600536808030651
PMID:21201231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2959344/
Abstract

The title compound, C(10)H(15)NO(4), also known as N-tert-butyl-oxycarbonyl-allohydr-oxy-l-proline lactone, is quite similar to N-acetyl-allohydr-oxy-l-proline lactone [Lenstra, Petit & Geise (1979 ▶). Cryst. Struct. Commun. 8, 1023-1029], whereby both carbonyl groups point roughly in the same direction because of the trans conformation of the peptide bond.

摘要

标题化合物C(10)H(15)NO(4)，也称为N-叔丁氧羰基-3-羟基-L-脯氨酸内酯，与N-乙酰基-3-羟基-L-脯氨酸内酯非常相似[伦斯特拉、佩蒂特和盖斯（1979年▶）。晶体结构通讯。8，1023 - 1029]，由于肽键的反式构象，两个羰基大致指向相同方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6d7/2959344/2c304193475b/e-64-o2039-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6d7/2959344/2c304193475b/e-64-o2039-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6d7/2959344/2c304193475b/e-64-o2039-fig1.jpg

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本文引用的文献

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A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
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Full stereochemical assignment and synthesis of the potent anthelmintic pyrrolobenzoxazine natural product CJ-12662.强效驱虫吡咯并苯并恶嗪天然产物CJ - 12662的全立体化学归属与合成
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The Cambridge Structural Database: a quarter of a million crystal structures and rising.剑桥结构数据库：拥有二十五万个晶体结构且数量不断增加。
Acta Crystallogr B. 2002 Jun;58(Pt 3 Pt 1):380-8. doi: 10.1107/s0108768102003890. Epub 2002 May 29.
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Short, highly efficient syntheses of protected 3-azido- and 4-azidoproline and their precursors.受保护的3-叠氮基脯氨酸和4-叠氮基脯氨酸及其前体的简短、高效合成方法。
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