Formation of dihydroxy derivative of ML-236B from ML-236B (compactin) by lipid peroxidation.
作者信息
Serizawa N, Nakahara K, Matsuoka T
机构信息
Fermentation Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1990 Aug;43(8):1031-3. doi: 10.7164/antibiotics.43.1031.
PMID:2120167
Abstract
摘要
相似文献
1
Formation of dihydroxy derivative of ML-236B from ML-236B (compactin) by lipid peroxidation.
J Antibiot (Tokyo). 1990 Aug;43(8):1031-3. doi: 10.7164/antibiotics.43.1031.
2
Lipid lowering drugs.降脂药物。
BMJ. 1990 May 5;300(6733):1195. doi: 10.1136/bmj.300.6733.1195-b.
3
Purification and characterization of cytochrome P-450sca from Streptomyces carbophilus. ML-236B (compactin) induces a cytochrome P-450sca in Streptomyces carbophilus that hydroxylates ML-236B to pravastatin sodium (CS-514), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase.嗜碳链霉菌中细胞色素P-450sca的纯化与特性分析。ML-236B（美伐他汀）可诱导嗜碳链霉菌产生一种细胞色素P-450sca，该细胞色素可将ML-236B羟化为普伐他汀钠（CS-514），一种3-羟基-3-甲基戊二酰辅酶A还原酶的组织选择性抑制剂。
Eur J Biochem. 1989 Oct 1;184(3):707-13. doi: 10.1111/j.1432-1033.1989.tb15070.x.
4
3 alpha-Hydroxy-ML-236B (3 alpha-hydroxycompactin), microbial transformation product of ML-236B (compactin).
J Antibiot (Tokyo). 1983 May;36(5):608-10. doi: 10.7164/antibiotics.36.608.
5
Microbial phosphorylation of compactin (ML-236B) and related compounds.
J Antibiot (Tokyo). 1985 Mar;38(3):328-32. doi: 10.7164/antibiotics.38.328.
6
Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B).ML-236B（美伐他汀）和莫纳可林K（MB-530B）的微生物羟基化作用
J Antibiot (Tokyo). 1983 May;36(5):604-7. doi: 10.7164/antibiotics.36.604.
7
Microbial hydroxylation of compactin (ML-236B) and monacolin K.
J Antibiot (Tokyo). 1985 May;38(5):605-9. doi: 10.7164/antibiotics.38.605.
8
Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.普伐他汀钠（一种3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂）对体内胆固醇合成的组织选择性抑制作用。
Biochim Biophys Acta. 1990 Jul 16;1045(2):115-20. doi: 10.1016/0005-2760(90)90139-o.
9
Taxonomy of actinomycetes capable of hydroxylation of ML-236B (compactin).
J Antibiot (Tokyo). 1983 Sep;36(9):1176-83. doi: 10.7164/antibiotics.36.1176.
10
Microbial conversion of compactin (ML-236B) to ML-236A.
J Antibiot (Tokyo). 1986 Nov;39(11):1574-7. doi: 10.7164/antibiotics.39.1574.
Zotero 插件