• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

4-（9-蒽基）-1-（4-甲氧基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮

4-(9-Anthr-yl)-1-(4-methoxy-phen-yl)spiro-[azetidin-3,9'-xanthen]-2-one.

作者信息

Akkurt Mehmet, Karaca Selvi, Jarrahpour Aliasghar, Ebrahimi Edris, Büyükgüngör Orhan

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Apr 26;64(Pt 5):o902-3. doi: 10.1107/S1600536808010908.

DOI:10.1107/S1600536808010908
PMID:21202385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2961274/
Abstract

In the title mol-ecule, C(36)H(25)NO(3), the β-lactam ring is essentially planar, with a dihedral angle of 3.3 (2)° between the two separate three-atom N/C/C planes. The β-lactam ring makes dihedral angles of 28.45 (14), 87.4 (1) and 51.8 (1)° with the mean planes of the benzene, xanthene and anthracene ring systems, respectively. In addition to a weak intra-molecular C-H⋯N hydrogen bond, the crystal structure is stabilized by two weak inter-molecular C-H⋯O hydrogen bonds.

摘要

在标题分子C(36)H(25)NO(3)中，β-内酰胺环基本呈平面状，两个独立的三原子N/C/C平面之间的二面角为3.3 (2)°。β-内酰胺环与苯、呫吨和蒽环系统的平均平面的二面角分别为28.45 (14)°、87.4 (1)°和51.8 (1)°。除了一个弱的分子内C-H⋯N氢键外，晶体结构还通过两个弱的分子间C-H⋯O氢键得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93df/2961274/f88eb7ddd572/e-64-0o902-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93df/2961274/0821a9a77349/e-64-0o902-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93df/2961274/f88eb7ddd572/e-64-0o902-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93df/2961274/0821a9a77349/e-64-0o902-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93df/2961274/f88eb7ddd572/e-64-0o902-fig2.jpg

相似文献

1
4-(9-Anthr-yl)-1-(4-methoxy-phen-yl)spiro-[azetidin-3,9'-xanthen]-2-one.4-（9-蒽基）-1-（4-甲氧基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2008 Apr 26;64(Pt 5):o902-3. doi: 10.1107/S1600536808010908.
2
4-(9-Anthr-yl)-1-(2-methoxy-phen-yl)spiro-[azetidin-3,9'-xanthen]-2-one.4-（9-蒽基）-1-（2-甲氧基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 28;65(Pt 3):o626-7. doi: 10.1107/S1600536809005200.
3
4-(9-Anthr-yl)-1-(3-bromo-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.4-（9-蒽基）-1-（3-溴苯基）螺-[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 26;65(Pt 10):o2522-3. doi: 10.1107/S1600536809037830.
4
4-(9-Anthr-yl)-1-(1-naphth-yl)spiro-[azetidine-3,9'-xanthen]-2-one n-hexane hemisolvate.4-（9-蒽基）-1-（1-萘基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮正己烷半溶剂化物
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 29;64(Pt 12):o2466-7. doi: 10.1107/S1600536808039305.
5
4-(9-Anthr-yl)-1-phenylspiro-[azetidine-3,9'-xanthen]-2-one.4-（9-蒽基）-1-苯基螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 11;65(Pt 3):o501-2. doi: 10.1107/S1600536809004255.
6
1-(Morpholin-4-yl)-4-(2-nitro-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.1-（吗啉-4-基）-4-（2-硝基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2014 Jun 14;70(Pt 7):o772-3. doi: 10.1107/S1600536814013464. eCollection 2014 Jul 1.
7
4-(9-Anthr-yl)-1-(2,4-dimethoxy-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.4-（9-蒽基）-1-（2,4-二甲氧基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 20;65(Pt 7):o1623-4. doi: 10.1107/S1600536809022739.
8
1-[3-(Morpholin-4-yl)prop-yl]-4-(3-nitro-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.1-[3-(吗啉-4-基)丙基]-4-(3-硝基苯基)螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2014 Feb 28;70(Pt 3):o369-70. doi: 10.1107/S160053681400419X. eCollection 2014 Mar 1.
9
Methyl 3-(4-bromo-phen-yl)-2-(1H-indol-3-ylmeth-yl)-5-[1-(4-methoxy-phen-yl)-4-oxo-2-phenyl-azetidin-2-yl]-4-nitro-pyrrolidine-2-carboxyl-ate.3-(4-溴苯基)-2-(1H-吲哚-3-基甲基)-5-[1-(4-甲氧基苯基)-4-氧代-2-苯基氮杂环丁烷-2-基]-4-硝基吡咯烷-2-羧酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2008 May 17;64(Pt 6):o1095-6. doi: 10.1107/S1600536808014190.
10
2-(2,4-Dichloro-phen-yl)-3-[5-(4-methoxy-phen-yl)-1,3,4-thia-diazol-2-yl]-1,3-thia-zolidin-4-one.2-（2,4-二氯苯基）-3-[5-（4-甲氧基苯基）-1,3,4-噻二唑-2-基]-1,3-噻唑烷-4-酮
Acta Crystallogr Sect E Struct Rep Online. 2008 Apr 4;64(Pt 5):o795. doi: 10.1107/S1600536808008465.

引用本文的文献

1
1-(Morpholin-4-yl)-4-(2-nitro-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.1-（吗啉-4-基）-4-（2-硝基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2014 Jun 14;70(Pt 7):o772-3. doi: 10.1107/S1600536814013464. eCollection 2014 Jul 1.
2
1-[3-(Morpholin-4-yl)prop-yl]-4-(3-nitro-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.1-[3-(吗啉-4-基)丙基]-4-(3-硝基苯基)螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2014 Feb 28;70(Pt 3):o369-70. doi: 10.1107/S160053681400419X. eCollection 2014 Mar 1.
3
3-(4-Chloro-phen-oxy)-1-(4-meth-oxy-phen-yl)-4-(4-nitro-phen-yl)azetidin-2-one.

本文引用的文献

1
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
2
Spiro beta-lactams as beta-turn mimetics. Design, synthesis, and NMR conformational analysis.
J Org Chem. 2001 Sep 21;66(19):6333-8. doi: 10.1021/jo015714m.
3-（4-氯苯氧基）-1-（4-甲氧基苯基）-4-（4-硝基苯基）氮杂环丁烷-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 May 1;67(Pt 5):o1101-2. doi: 10.1107/S1600536811013018. Epub 2011 Apr 13.
4
4-(9-Anthr-yl)-1-(2,4-dimethoxy-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.4-（9-蒽基）-1-（2,4-二甲氧基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 20;65(Pt 7):o1623-4. doi: 10.1107/S1600536809022739.
5
4-(9-Anthr-yl)-1-(2-methoxy-phen-yl)spiro-[azetidin-3,9'-xanthen]-2-one.4-（9-蒽基）-1-（2-甲氧基苯基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 28;65(Pt 3):o626-7. doi: 10.1107/S1600536809005200.
6
4-(9-Anthr-yl)-1-phenylspiro-[azetidine-3,9'-xanthen]-2-one.4-（9-蒽基）-1-苯基螺[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 11;65(Pt 3):o501-2. doi: 10.1107/S1600536809004255.
7
4-(9-Anthr-yl)-1-(1-naphth-yl)spiro-[azetidine-3,9'-xanthen]-2-one n-hexane hemisolvate.4-（9-蒽基）-1-（1-萘基）螺[氮杂环丁烷-3,9'-呫吨]-2-酮正己烷半溶剂化物
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 29;64(Pt 12):o2466-7. doi: 10.1107/S1600536808039305.
8
7-Benzenesulfonamido-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid monohydrate.7-苯磺酰胺基-3-甲基-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸一水合物
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 9;66(Pt 1):o73-4. doi: 10.1107/S1600536809051769.
9
4-(9-Anthr-yl)-1-(3-bromo-phen-yl)spiro-[azetidine-3,9'-xanthen]-2-one.4-（9-蒽基）-1-（3-溴苯基）螺-[氮杂环丁烷-3,9'-呫吨]-2-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 26;65(Pt 10):o2522-3. doi: 10.1107/S1600536809037830.
10
Synthesis of some new mono- and bis-polycyclic aromatic spiro and bis-nonspiro-beta-lactams.一些新的单环和双环芳族螺和双非螺β-内酰胺的合成。
Molecules. 2010 Jan 22;15(1):515-31. doi: 10.3390/molecules15010515.