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3-（4-氯苯氧基）-1-（4-甲氧基苯基）-4-（4-硝基苯基）氮杂环丁烷-2-酮

3-(4-Chloro-phen-oxy)-1-(4-meth-oxy-phen-yl)-4-(4-nitro-phen-yl)azetidin-2-one.

作者信息

Butcher Ray J, Akkurt Mehmet, Jarrahpour Aliasghar, Badrabady Seid Ali Torabi

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 May 1;67(Pt 5):o1101-2. doi: 10.1107/S1600536811013018. Epub 2011 Apr 13.

DOI:10.1107/S1600536811013018
PMID:21754420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3089293/
Abstract

In the title compound, C(22)H(17)ClN(2)O(5), the nearly planar four-membered β-lactam ring [maximum deviation of 0.016 (1) for the N atom] makes dihedral angles of 53.07 (9), 73.19 (9) and 6.61 (9)° with the chloro-, nitro- and meth-oxy-benzene rings, respectively. The crystal structure is stabilized by C-H⋯O hydrogen bonds, a weak C-H⋯π inter-action and a π-π stacking inter-action [centroid-centroid distance = 3.6513 (8) Å] between the meth-oxy-benzene rings of inversion-related mol-ecules.

摘要

在标题化合物C₂₂H₁₇ClN₂O₅中，近乎平面的四元β-内酰胺环（N原子的最大偏差为0.016 (1) Å）与氯苯环、硝基苯环和甲氧基苯环的二面角分别为53.07 (9)°、73.19 (9)°和6.61 (9)°。晶体结构通过C—H⋯O氢键、弱C—H⋯π相互作用以及反演相关分子的甲氧基苯环之间的π-π堆积相互作用[质心-质心距离 = 3.6513 (8) Å]得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4363/3089293/ae157d03a6f2/e-67-o1101-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4363/3089293/f695837c91ea/e-67-o1101-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4363/3089293/ae157d03a6f2/e-67-o1101-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4363/3089293/f695837c91ea/e-67-o1101-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4363/3089293/ae157d03a6f2/e-67-o1101-fig2.jpg

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