1-苯基-6,7,8,9-六氢-1H,5H-环庚并-[1',2':2,3]吡啶并[6,5-c]吡唑-4-胺：一种新的他克林类似物。
1-Phenyl-6,7,8,9-hexa-hydro-1H,5H-cyclo-hepta-[1',2':2,3]pyrido[6,5-c]pyrazol-4-amine: a new tacrine analogue.
作者信息
Zhang Lijun, Shi Daxin, Li Jiarong, Zhang Ling, Fan Yanqiu
机构信息
School of Chemical Engineering and the Environment, Beijing Institute of Technology, Beijing 100081, People's Republic of China.
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2008 May 10;64(Pt 6):o1056. doi: 10.1107/S1600536808013366.
The title compound, C(17)H(18)N(4), contains a pyrazolopyridine system fused with a seven-membered carbocyclic ring. The pyrazole ring is coplanar with the pyridine ring, while the phenyl ring is twisted by a dihedral angle of 14.38 (14)° with respect to the pyridine ring. The seven-membered ring displays a chair conformation. The packing is stabilized by N-H⋯N hydrogen bonds and N-H⋯π(arene) inter-actions.
标题化合物C(17)H(18)N(4)包含一个与七元碳环稠合的吡唑并吡啶体系。吡唑环与吡啶环共面，而苯环相对于吡啶环扭转了14.38 (14)°的二面角。七元环呈椅式构象。堆积通过N-H⋯N氢键和N-H⋯π(芳烃)相互作用得以稳定。
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