• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

1-[2-(3,4-二氯-苄氧基)-2-苯基-乙基]-1H-苯并咪唑

1-[2-(3,4-Dichloro-benz-yloxy)-2-phenyl-ethyl]-1H-benzimidazole.

作者信息

Ozel Güven Ozden, Erdoğan Taner, Coles Simon J, Hökelek Tuncer

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 26;64(Pt 8):o1588-9. doi: 10.1107/S1600536808022629.

DOI:10.1107/S1600536808022629
PMID:21203286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2962124/
Abstract

In the mol-ecule of the title compound, C(22)H(18)Cl(2)N(2)O, the planar benzimidazole ring system is oriented with respect to the phenyl and dichloro-benzene rings at dihedral angles of 12.73 (3) and 36.57 (4)°, respectively. The dihedral angle between the dichloro-benzene and phenyl rings is 29.95 (6)°. There are C-H⋯π contacts between the benzimidazole and dichloro-benzene rings, between the benzimidazole and phenyl rings, and between a methylene group and the dichlorobenzene ring.

摘要

在标题化合物C₂₂H₁₈Cl₂N₂O的分子中，平面苯并咪唑环系统相对于苯环和二氯苯环的二面角分别为12.73（3）°和36.57（4）°。二氯苯环与苯环之间的二面角为29.95（6）°。苯并咪唑环与二氯苯环之间、苯并咪唑环与苯环之间以及一个亚甲基与二氯苯环之间存在C—H⋯π相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae0/2962124/c8ff494beb2b/e-64-o1588-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae0/2962124/c8ff494beb2b/e-64-o1588-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae0/2962124/c8ff494beb2b/e-64-o1588-fig1.jpg

相似文献

1
1-[2-(3,4-Dichloro-benz-yloxy)-2-phenyl-ethyl]-1H-benzimidazole.1-[2-(3,4-二氯-苄氧基)-2-苯基-乙基]-1H-苯并咪唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 26;64(Pt 8):o1588-9. doi: 10.1107/S1600536808022629.
2
1-[2-(2,6-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-benzimidazole.1-[2-(2,6-二氯苄氧基)-2-(2-呋喃基)乙基]-1H-苯并咪唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 9;64(Pt 8):o1437. doi: 10.1107/S1600536808020758.
3
1-[2-(2,4-Dichloro-benz-yloxy)-2-phenyl-ethyl]-1H-1,2,4-triazole.1-[2-(2,4-二氯苄氧基)-2-苯基乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 29;64(Pt 12):o2465. doi: 10.1107/S1600536808039196.
4
1-[2-(2,4-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-1,2,4-triazole.1-[2-(2,4-二氯苄氧基)-2-(2-呋喃基)乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 28;65(Pt 11):o2868-9. doi: 10.1107/S1600536809044018.
5
1-[2-(4-Fluoro-benz-yloxy)-2-phenyl-ethyl]-1H-benzimidazole.1-[2-(4-氟苯氧基)-2-苯基乙基]-1H-苯并咪唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 16;64(Pt 8):o1496-7. doi: 10.1107/S1600536808021326.
6
1-[2-(2,5-Dichloro-benz-yloxy)-2-phenyl-eth-yl]-1H-benzotriazole.1-[2-(2,5-二氯-苄氧基)-2-苯基-乙基]-1H-苯并三唑
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3177-8. doi: 10.1107/S1600536811044783. Epub 2011 Nov 5.
7
1-[2-(4-Bromo-benz-yloxy)-2-phenyl-ethyl]-1H-1,2,4-triazole.1-[2-(4-溴-苄氧基)-2-苯基-乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 13;64(Pt 10):o1914-5. doi: 10.1107/S1600536808027748.
8
1-[2-(2,6-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-1,2,4-triazole.1-[2-(2,6-二氯苄氧基)-2-(2-呋喃基)乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 12;66(Pt 1):o107-8. doi: 10.1107/S1600536809052568.
9
1-[2-(4-Chloro-benz-yloxy)-2-phenyl-ethyl]-1H-benzotriazole.
Acta Crystallogr Sect E Struct Rep Online. 2010 May 8;66(Pt 6):o1246-7. doi: 10.1107/S1600536810015692.
10
1,3-Bis(3-phenyl-prop-yl)benzimidazolium bromide monohydrate.1,3 - 双(3 - 苯基丙基)苯并咪唑溴化物一水合物
Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 27;64(Pt 10):o2019-20. doi: 10.1107/S1600536808030432.

引用本文的文献

1
1-{2-(4-Chloro-benz-yloxy)-2-[4-(mor-pho-lin-4-yl)phen-yl]eth-yl}-1H-benzimidazole propan-2-ol monosolvate.1-{2-(4-氯-苄氧基)-2-[4-(吗啉-4-基)苯基]乙基}-1H-苯并咪唑丙-2-醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 17;69(Pt 9):o1437-8. doi: 10.1107/S1600536813022599. eCollection 2013.
2
1-{2-Benz-yloxy-2-[4-(morpholin-4-yl)phen-yl]eth-yl}-1H-benzimidazole.1-{2-苄氧基-2-[4-(吗啉-4-基)苯基]乙基}-1H-苯并咪唑
Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o147-8. doi: 10.1107/S1600536812051306. Epub 2012 Dec 22.
3
1-(1H-Benzimidazol-1-ylmeth-yl)-3-[2-(di-isopropyl-amino)eth-yl]-1H-benzimid-azolium bromide 0.25-hydrate.

本文引用的文献

1
1-[2-(4-Fluoro-benz-yloxy)-2-phenyl-ethyl]-1H-benzimidazole.1-[2-(4-氟苯氧基)-2-苯基乙基]-1H-苯并咪唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 16;64(Pt 8):o1496-7. doi: 10.1107/S1600536808021326.
2
1-[2-(2,6-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-benzimidazole.1-[2-(2,6-二氯苄氧基)-2-(2-呋喃基)乙基]-1H-苯并咪唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 9;64(Pt 8):o1437. doi: 10.1107/S1600536808020758.
3
A short history of SHELX.SHELX简史。
1-(1H-苯并咪唑-1-基甲基)-3-[2-(二异丙基氨基)乙基]-1H-苯并咪唑溴化物0.25水合物
Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 6;65(Pt 4):o699-700. doi: 10.1107/S160053680900765X.
4
1-[2-(2,4-Dichloro-benz-yloxy)-2-phenyl-ethyl]-1H-1,2,4-triazole.1-[2-(2,4-二氯苄氧基)-2-苯基乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 29;64(Pt 12):o2465. doi: 10.1107/S1600536808039196.
5
1-[2-(2,6-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-1,2,4-triazole.1-[2-(2,6-二氯苄氧基)-2-(2-呋喃基)乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 12;66(Pt 1):o107-8. doi: 10.1107/S1600536809052568.
6
1-[2-(2,4-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-1,2,4-triazole.1-[2-(2,4-二氯苄氧基)-2-(2-呋喃基)乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 28;65(Pt 11):o2868-9. doi: 10.1107/S1600536809044018.
7
1-[2-(4-Bromo-benz-yloxy)-2-phenyl-ethyl]-1H-1,2,4-triazole.1-[2-(4-溴-苄氧基)-2-苯基-乙基]-1H-1,2,4-三唑
Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 13;64(Pt 10):o1914-5. doi: 10.1107/S1600536808027748.
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
4
Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers.一些新型苯基和苯并咪唑取代苄基醚的合成及其抗菌活性
Bioorg Med Chem Lett. 2007 Apr 15;17(8):2233-6. doi: 10.1016/j.bmcl.2007.01.061. Epub 2007 Jan 25.
5
Preparation and crystal characterization of a polymorph, a monohydrate, and an ethyl acetate solvate of the antifungal fluconazole.抗真菌药氟康唑的一种多晶型物、一水合物及乙酸乙酯溶剂化物的制备与晶体表征
J Pharm Sci. 2004 Mar;93(3):601-11. doi: 10.1002/jps.10541.
6
The antifungal drug clotrimazole.
Acta Crystallogr C. 1998 Nov 15;54 ( Pt 11):1675-7. doi: 10.1107/s0108270198006386.