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电光协同技术:一种治疗皮肤老化的新型有效非侵入性方法。

Electro-optical Synergy Technique: A New and Effective Nonablative Approach to Skin Aging.

作者信息

El-Domyati Moetaz, El-Ammawi Tarek S, Medhat Walid, Moawad Osama, Mahoney My G, Uitto Jouni

出版信息

J Clin Aesthet Dermatol. 2010 Dec;3(12):22-30.

Abstract

OBJECTIVES

Electro-optical synergy technology is one of the most recently described methods for nonablative skin rejuvenation. The aim of this study is to evaluate the effects of electro-optical synergy on connective tissue composition by histological and immunohistochemical techniques coupled with computerized morphometric analysis.

DESIGN

A prospective clinical study.

PARTICIPANTS

Six volunteers with Fitzpatrick skin types 3 to 4 and Glogau class I to II wrinkles were subjected to three months (6 sessions at 2-week intervals) of electro-optical synergy treatment.

MEASUREMENTS

Standard photographs and skin biopsies were obtained at baseline as well as three and six months after the start of treatment. The authors performed quantitative evaluation of total elastin, tropoelastin, collagen types I, III, and VII, and newly synthesized collagen.

RESULTS

Noticeable clinical and histological improvement was observed after electro-optical synergy treatment. A statistically significant increase in the means of collagen types I, III, and VII, as well as newly synthesized collagen, together with increased levels of tropoelastin, were detected, while the mean level of total elastin was significantly decreased at the end of treatment and three months post-treatment.

CONCLUSION

Electro-optical synergy is an effective treatment for contouring facial skin laxity. This modality stimulates the repair processes and reverses the clinical, as well as the histopathological, signs of aging with the advantage of being a relatively risk-free procedure with minimal patient recovery time.

摘要

目的

电光协同技术是最近描述的非剥脱性皮肤年轻化方法之一。本研究的目的是通过组织学和免疫组织化学技术结合计算机形态计量分析来评估电光协同对结缔组织成分的影响。

设计

一项前瞻性临床研究。

参与者

6名皮肤类型为Fitzpatrick 3至4型、皱纹为Glogau I至II级的志愿者接受了为期三个月(每2周进行6次治疗)的电光协同治疗。

测量

在基线以及治疗开始后3个月和6个月时获取标准照片和皮肤活检样本。作者对总弹性蛋白、原弹性蛋白、I型、III型和VII型胶原蛋白以及新合成的胶原蛋白进行了定量评估。

结果

电光协同治疗后观察到明显的临床和组织学改善。检测到I型、III型和VII型胶原蛋白以及新合成胶原蛋白的平均值有统计学意义的增加,同时原弹性蛋白水平升高,而治疗结束时和治疗后3个月总弹性蛋白的平均水平显著降低。

结论

电光协同是改善面部皮肤松弛的有效治疗方法。这种治疗方式刺激修复过程,逆转衰老的临床和组织病理学迹象,优点是相对无风险且患者恢复时间最短。

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Nonablative tissue remodeling and photorejuvenation.非剥脱性组织重塑与光嫩肤
Clin Dermatol. 2007 Sep-Oct;25(5):474-9. doi: 10.1016/j.clindermatol.2007.05.006.

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