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人类免疫缺陷病毒 I 型感染南非儿童的巨细胞病毒视网膜炎。

Presumed cytomegalovirus retinitis in human immunodeficiency virus type I-infected South African children.

机构信息

Department of Paediatrics and Child Health, Tygerberg Children's Hospital, Stellenbosch University, Cape Town, South Africa.

出版信息

Pediatr Infect Dis J. 2011 Jun;30(6):539-40. doi: 10.1097/INF.0b013e3182092ca0.

DOI:10.1097/INF.0b013e3182092ca0
PMID:21206397
Abstract

In human immunodeficiency virus-infected children, cytomegalovirus causes retinitis alone, with dissemination, or with immune reconstitution inflammatory syndrome. We describe 6 severely immunosuppressed African children (median age, 6.7 months) with cytomegalovirus disease. Of the 6 children, 5 had clinical features suggesting ocular disease at presentation. The child in whom retinitis was detected through preemptive screening due to systemic disease achieved normal visual outcome.

摘要

在人类免疫缺陷病毒感染的儿童中,巨细胞病毒可单独引起视网膜炎,也可伴有播散性感染或免疫重建炎症综合征。我们描述了 6 例严重免疫抑制的非洲儿童(中位年龄 6.7 个月)的巨细胞病毒疾病。在这 6 例儿童中,5 例在就诊时出现了提示眼部疾病的临床表现。由于全身疾病而通过预先筛查发现视网膜炎的患儿获得了正常的视力结局。

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