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[母婴传播获得性艾滋病儿童的巨细胞病毒性视网膜炎]

[Cytomegalovirus retinitis in children with AIDS acquired through materno-fetal transmission].

作者信息

Bremond-Gignac D, Aron-Rosa D, Rohrlich P, Deplus S, Faye A, Vilmer E

机构信息

Service d'Ophtalmologie, Hôpital Robert Debré, Paris.

出版信息

J Fr Ophtalmol. 1995;18(2):91-5.

PMID:7738313
Abstract

PURPOSE

To describe the clinical feature and the outcome of CMV retinitis in children with vertically transmitted HIV infection.

RESULTS

Five case-reports of cytomegalovirus retinopathy are described. These children from eight month-old to seven and a half year-old (median age at diagnosis 52 months) had been perinatally contaminated by the human immuno-deficiency virus. The ophthalmic signs included only a red eye for one patient. The clinical signs were similar to the adult's retinopathy. At the opposite the differences were emphasized like the clinical onset with a delayed diagnosis. Mean follow-up since diagnosis is 8 months with 3 patients still alive.

CONCLUSION

CMV retinitis in vertically transmitted AIDS can occur early in childhood and must be checked systematically in the patients with low CD 4 count because of the usual asymptomatic onset.

摘要

目的

描述垂直传播的人类免疫缺陷病毒(HIV)感染儿童巨细胞病毒视网膜炎的临床特征及转归。

结果

描述了5例巨细胞病毒性视网膜炎的病例报告。这些儿童年龄从8个月至7岁半(诊断时的中位年龄为52个月),均在围产期感染了人类免疫缺陷病毒。眼科体征方面,仅1例患者表现为眼红。临床体征与成人视网膜炎相似。相反,差异也很明显,比如临床起病时诊断延迟。自诊断以来的平均随访时间为8个月,3例患者仍存活。

结论

垂直传播的艾滋病患儿巨细胞病毒视网膜炎可在儿童早期发生,由于通常起病无症状,对于CD4计数低的患者必须进行系统检查。

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