FAM联合辅助化疗治疗胃腺癌和肺腺癌后发生的急性非淋巴细胞白血病。
Acute non-lymphocytic leukemia following FAM combination adjuvant chemotherapy for gastric and lung adenocarcinoma.
作者信息
Bouillet T, Lepage E, Gisselbrecht C, Boiron M
机构信息
Department of Hematology, Hôpital Saint-Louis, Paris.
出版信息
Nouv Rev Fr Hematol (1978). 1990;32(3):207-9.
PMID:2120675
Abstract
We report 2 cases of acute non-lymphocytic leukemia with distinct clinical and karyotypic features shared by therapy-related acute non-lymphocytic leukemia occurring after adjuvant chemotherapy including 5-fluorouracil, doxorubicin and mitomycin C. Our observation suggests a causal relationship between exposure to mitomycin C and the occurrence of acute non-lymphocytic leukemia.
摘要
我们报告了2例急性非淋巴细胞白血病，其具有与包括5-氟尿嘧啶、阿霉素和丝裂霉素C在内的辅助化疗后发生的治疗相关性急性非淋巴细胞白血病相同的独特临床和核型特征。我们的观察表明，接触丝裂霉素C与急性非淋巴细胞白血病的发生之间存在因果关系。
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