Complementary Medicine, Peninsula Medical School, University of Exeter, 25 Victoria Park Road, Exeter, EX2 4NT, UK.
Clin Rheumatol. 2011 May;30(5):593-600. doi: 10.1007/s10067-010-1663-4. Epub 2011 Jan 5.
To promote an independent and critical evaluation of 11 randomised clinical trials (RCTs) of chiropractic funded by the National Centre for Complementary and Alternative Medicine (NCCAM). Electronic searches were conducted to identify all relevant RCTs. Key data were extracted and the risk of bias of each study was determined. Ten RCTs were included, mostly related to chiropractic spinal manipulation for musculoskeletal problems. Their quality was frequently questionable. Several RCTs failed to report adverse effects and the majority was not described in sufficient detail to allow replication. The criticism repeatedly aimed at NCCAM seems justified, as far as their RCTs of chiropractic is concerned. It seems questionable whether such research is worthwhile.
对美国国家补充与替代医学中心（NCCAM）资助的 11 项整脊随机临床试验（RCT）进行独立和批判性评估。通过电子检索来确定所有相关的 RCT。提取关键数据，并确定每项研究的偏倚风险。纳入了 10 项 RCT，主要涉及针对肌肉骨骼问题的整脊脊柱手法治疗。其质量经常受到质疑。一些 RCT 未能报告不良反应，而且大多数 RCT 没有详细描述，难以重复。就 NCCAM 的整脊 RCT 而言，对其的批评似乎是有道理的。这样的研究是否值得，值得怀疑。
