Weidner W, Garbe C, Weissbach L, Harbrecht J, Kleinschmidt K, Schiefer H G, Friedrich H J
Urologische Klinik, Justus Liebig Universität Giessen.
Urologe A. 1990 Sep;29(5):277-80.
A total of 70 men suffering from uncomplicated acute unilateral epididymitis were enrolled in a prospective study. They were treated initially with 2 x 200 mg ofloxacin p.o. per day for 14 days, after which the spermatological examination was repeated for each. Ejaculate quality, i.e. density, motility, and morphology of spermatozoa, was determined on the last day of therapy, i.e. after 14 days, and again after 6 and 12 weeks. In most patients, initially decreased sperm counts increased significantly and global motility improved, while the numbers of abnormal spermatozoa decreased. Only in a few cases were azoospermia, kryptozoospermia, consistently reduced motility, and constant or even increasing numbers of deformed spermatozoa observed.
共有70名患单纯性急性单侧附睾炎的男性参与了一项前瞻性研究。他们最初接受每日2次、每次200毫克氧氟沙星口服治疗，疗程为14天，之后对每人重复进行精液学检查。在治疗的最后一天，即14天后，以及在6周和12周后，分别测定精液质量，即精子密度、活力和形态。在大多数患者中，最初降低的精子计数显著增加，总体活力改善，而异常精子数量减少。仅在少数病例中观察到无精子症、隐匿精子症、持续降低的活力以及畸形精子数量持续或甚至增加的情况。
