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表面等离子体分光角反射光谱分析:实时测量、分辨率限制及在生物传感中的应用。

Analysis of surface plasmon spectro-angular reflectance spectrum: real-time measurement, resolution limits, and applications to biosensing.

机构信息

Photonic Systems Group, Department of Electrical and Computer Engineering, McConnell Building, McGill University, Montreal, Quebec, H3A 2A7 Canada.

出版信息

Opt Lett. 2011 Jan 1;36(1):46-8. doi: 10.1364/OL.36.000046.

DOI:10.1364/OL.36.000046
PMID:21209682
Abstract

A surface plasmon biosensing technique based on real-time measurement of the spectro-angular reflectance spectrum of a gold surface is presented. A significant improvement in refractive index resolution and drift compensation has been achieved for the spectro-angular technique to demonstrate a biosensing platform that is, in addition, applicable to plasmonic bandgap measurements. Instrumental improvements are detailed and constants for the model bovine serum albumin (BSA):oxacillin bioassay are presented.

摘要

提出了一种基于金表面实时测量光谱角反射率谱的表面等离子体生物传感技术。该光谱角技术在折射率分辨率和漂移补偿方面有了显著的改进,展示了一个生物传感平台,此外还适用于等离子体带隙测量。详细介绍了仪器改进,并给出了模型牛血清白蛋白(BSA):苯唑西林生物测定的常数。

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