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血清催乳素正常的高催乳素血症:其临床意义。

Hyperprolactinemia with normal serum prolactin: Its clinical significance.

作者信息

Agarwal Manika, Das Ananya, Singh Santa A

机构信息

Department of Obstetrics and Gynecology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Mawdiangdiang, Shillong - 793 018, Meghalaya, India.

出版信息

J Hum Reprod Sci. 2010 May;3(2):111-2. doi: 10.4103/0974-1208.69334.

Abstract

Amenorrhea and infertility with an added feature of galactorrhea makes a provisional diagnosis of hyperprolactinemia. But again, normal serum prolactin with all clinical features of hyperprolactinemia might question the diagnosis and further management. The answer lies in the heterogeneity of the peptide hormone - the immunoactive and the bioactive forms. This has been further illustrated with the help of a case which had been treated with cabergoline.

摘要

闭经、不孕并伴有溢乳症状可初步诊断为高催乳素血症。然而,血清催乳素水平正常但却具备高催乳素血症的所有临床特征,这可能会对诊断及后续治疗提出质疑。答案在于这种肽类激素的异质性——免疫活性形式和生物活性形式。通过一个使用卡麦角林治疗的病例进一步说明了这一点。

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本文引用的文献

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Nipple discharge.乳头溢液
Obstet Gynecol Clin North Am. 2002 Mar;29(1):21-9. doi: 10.1016/s0889-8545(03)00049-4.
3
Bromocriptine for unexplained subfertility in women.溴隐亭治疗女性不明原因的生育力低下
Cochrane Database Syst Rev. 2000(2):CD000044. doi: 10.1002/14651858.CD000044.
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Incidence of galactorrhea.溢乳发生率。
JAMA. 1976 Dec 13;236(24):2747.

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