Pickard J D, Bailey S, Sanderson H, Rees M, Garfield J S
University Clinical Neurosciences Group, Wessex Neurological Centre, Southampton General Hospital.
BMJ. 1990 Sep 29;301(6753):629-35. doi: 10.1136/bmj.301.6753.629.
To determine the cost of averting death or severe disability by neurosurgical intervention.
Retrospective analysis of one year's admissions for neurosurgery; comparison of outcome with expected outcome in the absence of neurosurgical intervention and with the cost of neurosurgery.
Wessex Neurological Centre.
1026 Patients were admitted to the neurosurgical service in 1984. Of 1185 admissions, 978 case records were available and outcome was known in 919.
Outcome was assessed with the Glasgow outcome scale, modified as necessary, from the case notes, or by letter follow up to the general practitioner. Expected outcomes for each of the 54 diagnoses were derived from both published reports where available and an expert panel of 18 consultant neurosurgeons. The cost of the neurosurgical service for 1983-4 was known from a separate study and the cost per patient was calculated using the length of stay.
The cost of neurosurgery in 1983-4 was 1.8 million pounds. In all, 243 deaths or severe disabilities were estimated to have been averted at an average cost of 7325 pounds (range 5000 pounds to 70,000 pounds). The overall cost per quality adjusted life year (QALY) was 350 pounds (range 34 pounds to greater than 400,000 pounds). The cost of long term care for severely disabled survivors is at least 18-fold greater than the cost of neurosurgical intervention to avert such disability.
In Britain neurosurgery is not expensive in comparison with the costs and benefits of other areas of medicine, and the cost per QALY is unexpectedly low except for severe diffuse head injury, malignant brain tumors, and cerebral metastases. The neurosurgical budget should be assessed in the context of managing a patient in hospital and subsequently in the community.
确定通过神经外科干预避免死亡或严重残疾的成本。
对一年的神经外科住院病例进行回顾性分析;将结果与未进行神经外科干预时的预期结果以及神经外科手术成本进行比较。
韦塞克斯神经中心。
1984年有1026名患者入住神经外科。在1185例住院病例中,有978份病例记录可用,其中919例的结果已知。
根据病例记录,必要时采用改良的格拉斯哥预后量表评估结果,或通过向全科医生随访信件进行评估。54种诊断中每种诊断的预期结果均来自已发表的报告(如有)以及由18名神经外科顾问组成的专家小组。1983 - 1984年神经外科服务的成本来自另一项单独研究,每位患者的成本通过住院时间计算得出。
1983 - 1984年神经外科手术成本为180万英镑。总计估计避免了243例死亡或严重残疾,平均成本为7325英镑(范围为5000英镑至70000英镑)。每个质量调整生命年(QALY)的总成本为350英镑(范围为34英镑至大于400000英镑)。严重残疾幸存者的长期护理成本比避免此类残疾的神经外科干预成本至少高18倍。
在英国,与其他医学领域的成本和效益相比,神经外科手术并不昂贵,除了严重弥漫性脑损伤、恶性脑肿瘤和脑转移瘤外,每个QALY的成本出人意料地低。神经外科预算应在患者住院及随后在社区管理的背景下进行评估。