Mensink R P, Stolwijk A M, Katan M B
Department of Human Nutrition, Agricultural University, Wageningen, The Netherlands.
Eur J Clin Invest. 1990 Aug;20(4):463-9. doi: 10.1111/j.1365-2362.1990.tb01885.x.
The effect on blood pressure of monounsaturated and (n-6)polyunsaturated fatty acids was studied under strict dietary control in normotensive subjects. For 17 days 31 women and 27 men received a control diet providing 19.3% of energy as saturated fat. Then subjects were randomized over two test diets: one diet provided 15.1% of energy from monounsaturated and 7.9% from polyunsaturated fatty acids ('mono diet'), and the other diet provided 10.8% from monounsaturated and 12.7% from polyunsaturated fatty acids ('poly diet'). Saturated fat intake was now 12.8% on both diets. Mean blood pressure at the end of the control period was 116/69 mmHg for the mono group and 117/73 mmHg for the poly group. After 5 weeks on the test diet, blood pressure was 115/67 mmHg for the mono group and 117/72 mmHg for the poly group (difference in changes between the two diet groups was not significant). These findings suggest that at a high fat intake, linoleic acid, when providing more than 7.9% of energy intake, does not influence blood pressure relative to oleic acid in normotensive women and men.
在严格的饮食控制下,对血压正常的受试者研究了单不饱和脂肪酸和(n-6)多不饱和脂肪酸对血压的影响。31名女性和27名男性在17天内接受了一种对照饮食,该饮食提供占能量19.3%的饱和脂肪。然后,受试者被随机分配到两种试验饮食中:一种饮食提供占能量15.1%的单不饱和脂肪酸和7.9%的多不饱和脂肪酸(“单不饱和脂肪酸饮食”),另一种饮食提供占能量10.8%的单不饱和脂肪酸和12.7%的多不饱和脂肪酸(“多不饱和脂肪酸饮食”)。两种饮食中的饱和脂肪摄入量均为12.8%。在对照期结束时,单不饱和脂肪酸组的平均血压为116/69 mmHg,多不饱和脂肪酸组为117/73 mmHg。在试验饮食5周后,单不饱和脂肪酸组的血压为115/67 mmHg,多不饱和脂肪酸组为117/72 mmHg(两个饮食组之间的变化差异不显著)。这些发现表明,在高脂肪摄入情况下,当亚油酸提供的能量摄入量超过7.9%时,相对于油酸,它对血压正常的女性和男性的血压没有影响。