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[影响黑腹果蝇achaete-scute复合体等位基因表型表现的新突变的遗传分析]

[Genetic analysis of new mutations affecting the phenotypic manifestations of alleles from the achaete-scute complex in Drosophila melanogaster].

作者信息

Georgiev P G, Gerasimova T I

出版信息

Genetika. 1990 Jul;26(7):1221-9.

PMID:2121601
Abstract

The achaete-scute complex contains four homologous genes involved in formation of the central and periphery nervous system in Drosophila melanogaster. The achaete and scute mutations lead to reduction of bristles and hairs on head and thorax. We found mutations at three loci not analyzed earlier. The suppressor of scute mutations suppress phenotypic expression of the achaete and scute alleles. Mutations in two other genes, pseudoscute and microchaetae, induce bristles reduction, i.e. the changes typical of scute mutations. Possible role of these genes in development of nervous system is being discussed.

摘要

achaete-scute复合体包含四个同源基因,参与黑腹果蝇中枢和外周神经系统的形成。achaete和scute突变导致头部和胸部刚毛和毛发减少。我们发现了三个之前未分析过的基因座的突变。scute突变的抑制子抑制achaete和scute等位基因的表型表达。另外两个基因,即假scute和微刚毛的突变,会导致刚毛减少,即scute突变的典型变化。正在讨论这些基因在神经系统发育中的可能作用。

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