Georgiev P G
Genetika. 1990 Aug;26(8):1523-6.
The achaete-scute complex (AS-C) and the cut locus are involved in formation of the nervous system in Drosophila melanogaster. We found that several alleles of the AS-C modified the phenotypic expression of ct allele inducing the appearance of excisions and hair reduction on the external edge of the wing. The effect is a result of damage in correct expression of the scute locus. The effect of some other mutations on the ct6 expression was also described. The system can be used for analysis of interactions of the AS-C and some other genes in the wing imaginal disc.
achaete - scute复合体(AS - C)和cut基因座参与黑腹果蝇神经系统的形成。我们发现AS - C的几个等位基因改变了ct等位基因的表型表达,导致翅膀外缘出现切迹和毛发减少。这种效应是scute基因座正确表达受损的结果。还描述了其他一些突变对ct6表达的影响。该系统可用于分析AS - C与翅成虫盘上其他一些基因的相互作用。