University of Cambridge, Department of Physiology, Development and Neuroscience, Cambridge, UK.
Trends Cogn Sci. 2011 Feb;15(2):56-67. doi: 10.1016/j.tics.2010.12.004. Epub 2011 Jan 7.
Rapid advances have recently been made in understanding how value-based decision-making processes are implemented in the brain. We integrate neuroeconomic and computational approaches with evidence on the neural correlates of value and experienced pleasure to describe how systems for valuation and decision-making are organized in the prefrontal cortex of humans and other primates. We show that the orbitofrontal and ventromedial prefrontal (VMPFC) cortices compute expected value, reward outcome and experienced pleasure for different stimuli on a common value scale. Attractor networks in VMPFC area 10 then implement categorical decision processes that transform value signals into a choice between the values, thereby guiding action. This synthesis of findings across fields provides a unifying perspective for the study of decision-making processes in the brain.
近年来，人们在理解大脑中基于价值的决策过程是如何实现的方面取得了迅速进展。我们将神经经济学和计算方法与价值的神经相关物和体验到的快乐证据相结合，来描述人类和其他灵长类动物的前额叶皮层中用于估值和决策的系统是如何组织的。我们表明，眶额和腹内侧前额叶皮层（VMPFC）对不同刺激的预期价值、奖励结果和体验到的快乐进行计算，使用的是共同的价值尺度。然后，VMPFC 区域 10 中的吸引网络实施分类决策过程，将价值信号转化为对这些价值的选择，从而指导行动。这些跨领域的发现的综合提供了一个统一的视角，用于研究大脑中的决策过程。
