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以1,4-二氧六环为萃取溶剂的分光光度法测定片剂中的甲芬那酸

Spectrophotometric Assay of Mefenamic Acid in Tablets Using 1,4-dioxane as Solvent for Extraction.

作者信息

Mathai G, Moolayil J T, Jose K B, Sebastian V S

机构信息

Department of Chemistry, Sacred Heart College, Thevara, Kochi- 682 013, India.

出版信息

Indian J Pharm Sci. 2010 Jul;72(4):525-6. doi: 10.4103/0250-474X.73928.

Abstract

A spectrophotometric method of assay of mefenamic acid in tablets involving, dissolving the tablet powder in 1,4-dioxane and measuring the absorbance at 353.2 nm. The concentration of mefenamic acid is determined using the previously prepared calibration curve using standard solution of mefenamic acid in dioxane. The method was tested by assay of six different commercial tablets containing mefenamic acid.

摘要

一种分光光度法测定片剂中甲芬那酸的方法,该方法包括将片剂粉末溶解于1,4 - 二氧六环中,并在353.2 nm处测量吸光度。甲芬那酸的浓度通过使用先前制备的甲芬那酸在二氧六环中的标准溶液校准曲线来测定。该方法通过测定六种不同的含甲芬那酸市售片剂进行了测试。

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