Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.
Indian J Dermatol Venereol Leprol. 2011 Jan-Feb;77(1):28-36. doi: 10.4103/0378-6323.74970.
Lichen simplex chronicus (LSC) of the anogenital region, is a benign, extremely uncomfortable disease.
As very little is known about the cause of anogenital LSC (AGLSC), we undertook this study to determine various clinico-etiological factors involved in it and to assess the frequency of AGLSC.
This was a descriptive study, including 105 patients with AGLSC, who attended the Dermatology clinic in our institute from September 2007 to June 2009. Detailed history, physical examination, and relevant investigations were done. The collected data were tabulated and analyzed.
The frequency of AGLSC among patients presenting with anogenital pruritus was 2.54%. Primary AGLSC was more common than secondary AGLSC (69.5% vs. 30.5%). AGLSC manifested more commonly in males than in females (56.2% vs. 43.8%). The mean duration of the disease was 30.6 months. The common triggering factors for itching were sweating (41.9%), rubbing of thighs while walking for long distances (9.5%), and mental stress (5.7%). Pruritus of AGLSC was related to the intake of various food items in 37.1% of patients. In males, scrotum was the predominant site involved (89.8%), whereas in females, labia majora was the predominant site involved (78.2%). Nearly one-third of cases (30.5%) of AGLSC had some other dermatoses in the anogenital region.
Though psychological factors are thought to play an important role in disease causation and perpetuation among AGLSC patients, their significance could not be ascertained by us.
肛门生殖器部位慢性单纯性苔藓（LSC）是一种良性的、非常不适的疾病。
由于对肛门生殖器部位 LSC（AGLSC）的病因知之甚少，我们进行了这项研究，以确定其涉及的各种临床病因，并评估 AGLSC 的频率。
这是一项描述性研究，包括 2007 年 9 月至 2009 年 6 月在我们研究所皮肤科就诊的 105 例 AGLSC 患者。进行了详细的病史、体格检查和相关检查。收集的数据进行制表和分析。
在出现肛门生殖器瘙痒的患者中，AGLSC 的频率为 2.54%。原发性 AGLSC 比继发性 AGLSC 更常见（69.5%比 30.5%）。AGLSC 更常见于男性（56.2%比 43.8%）。疾病的平均持续时间为 30.6 个月。瘙痒的常见诱发因素包括出汗（41.9%）、长途行走时大腿摩擦（9.5%）和精神压力（5.7%）。瘙痒与 37.1%的患者摄入各种食物有关。在男性中，阴囊是主要受累部位（89.8%），而在女性中，大阴唇是主要受累部位（78.2%）。近三分之一（30.5%）的 AGLSC 病例在肛门生殖器区域有其他一些皮肤病。
尽管心理因素被认为在 AGLSC 患者的病因和持续中起着重要作用，但我们无法确定其重要性。
