Can Fam Physician. 1992 Sep;38:2084-92.
Multiple sclerosis, the most common disabling disease of the central nervous system affecting young adults, is diagnosed primarily from a history of typical relapsing and remitting white matter symptoms supported by objective signs. Multiple sclerosis may present in more insidious ways or may be mimicked by other diseases, which seemingly satisfy the diagnostic criteria of dissemination in time and space. Patients need psychological support to deal with an uncertain future. A multidisciplinary team approach can best manage both acute temporary disability and, often later, progressive physical and occasionally mental disability.
多发性硬化症是最常见的中青年中枢神经系统致残性疾病,主要根据典型的复发缓解型白质症状病史,结合客观体征进行诊断。多发性硬化症的表现可能较为隐匿,也可能被其他疾病模拟,这些疾病看似符合时间和空间上的扩散诊断标准。患者需要心理支持来应对不确定的未来。多学科团队方法可以最好地管理急性短暂性残疾,以及通常在稍后出现的进行性身体残疾,偶尔也有精神残疾。